(E)-1-tert-Butyl-2-(1-phenylpropan-2-yl)diazene

Base Information

• Chemical Name: (E)-1-tert-Butyl-2-(1-phenylpropan-2-yl)diazene
• CAS No.: 88630-75-5
• Molecular Formula: C13H20N2
• Molecular Weight: 204.315
• DSSTox Substance ID: DTXSID90525499
• Mol file: 88630-75-5.mol

Synonyms:88630-75-5;(E)-1-tert-Butyl-2-(1-phenylpropan-2-yl)diazene;DTXSID90525499

Chemical Property of (E)-1-tert-Butyl-2-(1-phenylpropan-2-yl)diazene

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 204.162648646
• Heavy Atom Count: 15
• Complexity: 197

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC1=CC=CC=C1)N=NC(C)(C)C

Technology Process of (E)-1-tert-Butyl-2-(1-phenylpropan-2-yl)diazene

There total 1 articles about (E)-1-tert-Butyl-2-(1-phenylpropan-2-yl)diazene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl bromide (100-39-0) + tert-butyl hydrazone of acetaldehyde (82571-41-3) → 2-(t-butylazo)-1-phenylpropane (88630-75-5)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) THF, 0 deg C, 10 min; -78 deg C, 2.) THF, -78 to 25 deg C, 3 h; 25 deg C, 18 h;

DOI:10.1016/S0040-4020(01)87647-X

Reference yield:

2-(t-butylazo)-1-phenylpropane (88630-75-5) → 1-phenyl-acetone (103-79-7,136675-26-8)

Guidance literature:

Multi-step reaction with 2 steps

1: TFA / CH₂Cl₂ / 18 h / 25 °C

2: 69 percent / oxalic acid, water / diethyl ether / 18 h

With water; oxalic acid; trifluoroacetic acid; In diethyl ether; dichloromethane;

DOI:10.1016/S0040-4020(01)87647-X

Reference yield:

2-(t-butylazo)-1-phenylpropane (88630-75-5) → N-tert-Butyl-N'-[1-methyl-2-phenyl-eth-(Z)-ylidene]-hydrazine (62204-41-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 25 ℃; for 18h;

DOI:10.1016/S0040-4020(01)87647-X

upstream raw materials:

benzyl bromide

tert-butyl hydrazone of acetaldehyde

Downstream raw materials:

N-tert-Butyl-N'-[1-methyl-2-phenyl-eth-(Z)-ylidene]-hydrazine

1-phenyl-acetone