(2-Amino-4,5-dimethoxyphenyl)(2,3-dihydro-1H-indol-1-yl)methanone

Base Information

Chemical Name:(2-Amino-4,5-dimethoxyphenyl)(2,3-dihydro-1H-indol-1-yl)methanone
CAS No.:88660-15-5
Molecular Formula:C17H18N2O3
Molecular Weight:298.342
Hs Code.:
DSSTox Substance ID:DTXSID60588591
Wikidata:Q82481350

Synonyms:88660-15-5;DTXSID60588591;(2-Amino-4,5-dimethoxyphenyl)(2,3-dihydro-1H-indol-1-yl)methanone;AKOS000146243

Suppliers and Price of (2-Amino-4,5-dimethoxyphenyl)(2,3-dihydro-1H-indol-1-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (2-Amino-4,5-dimethoxyphenyl)(2,3-dihydro-1H-indol-1-yl)methanone

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:298.13174244
Heavy Atom Count:22
Complexity:403

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)C(=O)N2CCC3=CC=CC=C32)N)OC

Technology Process of (2-Amino-4,5-dimethoxyphenyl)(2,3-dihydro-1H-indol-1-yl)methanone

There total 3 articles about (2-Amino-4,5-dimethoxyphenyl)(2,3-dihydro-1H-indol-1-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88660-14-4
1-(2-nitro-4,5-dimethoxybenzoyl)-indoline

: 88660-15-5
1-(2-amino-4,5-dimethoxybenzoyl)-indoline

Guidance literature:: With palladium on activated charcoal; ethanol; ethyl acetate; at 50 - 60 ℃; Hydrogenation;
DOI:10.1021/ja01597a078

Reference yield:

: 496-15-1
1-indoline

: 88660-15-5
1-(2-amino-4,5-dimethoxybenzoyl)-indoline

Guidance literature:: Multi-step reaction with 2 steps

1: 0.89 g / diethyl ether

2: H₂ / 10percent Pd-C / ethanol / 4 h / Heating

With hydrogen; palladium on activated charcoal; In diethyl ether; ethanol;
DOI:10.1016/S0031-9422(00)80167-3

Reference yield:

: 29568-78-3
4,5-dimethoxy-2-nitrobenzoyl chloride

: 88660-15-5
1-(2-amino-4,5-dimethoxybenzoyl)-indoline

Guidance literature:: Multi-step reaction with 2 steps

1: 0.89 g / diethyl ether

2: H₂ / 10percent Pd-C / ethanol / 4 h / Heating

With hydrogen; palladium on activated charcoal; In diethyl ether; ethanol;
DOI:10.1016/S0031-9422(00)80167-3