(4-Bromo-5-hydroxy-1-benzofuran-3-yl)(4-methoxyphenyl)methanone

Base Information

Chemical Name:(4-Bromo-5-hydroxy-1-benzofuran-3-yl)(4-methoxyphenyl)methanone
CAS No.:88673-81-8
Molecular Formula:C16H11BrO4
Molecular Weight:347.165
Hs Code.:
ChEMBL ID:CHEMBL1808013
DSSTox Substance ID:DTXSID90526007
Wikidata:Q82394087

Synonyms:88673-81-8;SCHEMBL290635;CHEMBL1808013;DTXSID90526007;(4-Bromo-5-hydroxy-1-benzofuran-3-yl)(4-methoxyphenyl)methanone

Suppliers and Price of (4-Bromo-5-hydroxy-1-benzofuran-3-yl)(4-methoxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (4-Bromo-5-hydroxy-1-benzofuran-3-yl)(4-methoxyphenyl)methanone

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:345.98407
Heavy Atom Count:21
Complexity:381

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=O)C2=COC3=C2C(=C(C=C3)O)Br

Technology Process of (4-Bromo-5-hydroxy-1-benzofuran-3-yl)(4-methoxyphenyl)methanone

There total 3 articles about (4-Bromo-5-hydroxy-1-benzofuran-3-yl)(4-methoxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.6%

: 17249-65-9
(5-hydroxy-benzofuran-3-yl)-(4-methoxyphenyl)-methanone

: 88673-81-8
(4-bromo-5-hydroxy-benzofuran-3-yl)-(4-methoxyphenyl)-methanone

Guidance literature:: With bromine; In acetic acid; for 5h; Ambient temperature;
DOI:10.1007/BF00505747

Reference yield: 10.0%

: 3958-82-5
2-bromo-1,4-benzoquinone

: 18096-70-3
3-(dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one

: 1254339-04-2
(6-bromo-5-hydroxy-benzofuran-3-yl)-(4-methoxyphenyl)-methanone

: 1254339-06-4
7-bromo-5-hydroxy-benzofuran-3-yl-(4-methoxyphenyl)-methanone

: 88673-81-8
(4-bromo-5-hydroxy-benzofuran-3-yl)-(4-methoxyphenyl)-methanone

Guidance literature:: In acetic acid; at 20 ℃; for 5h; Inert atmosphere;

Reference yield:

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 1254339-04-2
(6-bromo-5-hydroxy-benzofuran-3-yl)-(4-methoxyphenyl)-methanone

: 1254339-06-4
7-bromo-5-hydroxy-benzofuran-3-yl-(4-methoxyphenyl)-methanone

: 88673-81-8
(4-bromo-5-hydroxy-benzofuran-3-yl)-(4-methoxyphenyl)-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 20 h / 150 °C / Inert atmosphere

2: acetic acid / 5 h / 20 °C / Inert atmosphere

With acetic acid; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.05.129