2-((4-Nitrophenyl)thio)isoindoline-1,3-dione

Base Information

Chemical Name:2-((4-Nitrophenyl)thio)isoindoline-1,3-dione
CAS No.:88683-47-0
Molecular Formula:C14H8N2O4S
Molecular Weight:300.295
Hs Code.:
DSSTox Substance ID:DTXSID50500429
Wikidata:Q82352006

Synonyms:2-((4-Nitrophenyl)thio)isoindoline-1,3-dione;88683-47-0;DTXSID50500429;2-[(4-Nitrophenyl)sulfanyl]-1H-isoindole-1,3(2H)-dione

Suppliers and Price of 2-((4-Nitrophenyl)thio)isoindoline-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-((4-Nitrophenyl)thio)isoindoline-1,3-dione

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:300.02047791
Heavy Atom Count:21
Complexity:432

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)SC3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 2-((4-Nitrophenyl)thio)isoindoline-1,3-dione

There total 4 articles about 2-((4-Nitrophenyl)thio)isoindoline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 136918-14-4,85-41-6
phthalimide

: 1849-36-1
para-nitrobenzenethiol

: 88683-47-0
2-((4-nitrophenyl)thio)isoindoline-1,3-dione

Guidance literature:: phthalimide; para-nitrobenzenethiol; With pyridine; In acetonitrile;

With bromine; In acetonitrile;
DOI:10.1080/10426507.2011.561457

Reference yield:

: 7764-30-9
2,2'-disulfanediylbis(isoindoline-1,3-dione)

: 88683-47-0
2-((4-nitrophenyl)thio)isoindoline-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuryl dichloride; pyridine / dichloromethane / 48 h / 20 °C / Inert atmosphere; Schlenk technique

2.1: magnesium; lithium chloride; iodine / tetrahydrofuran / 2.5 h / 55 °C / Inert atmosphere; Schlenk technique

2.2: 1 h / 0 - 25 °C / Inert atmosphere; Schlenk technique

2.3: 0.83 h / 0 - 25 °C / Inert atmosphere; Schlenk technique

With pyridine; sulfuryl dichloride; iodine; magnesium; lithium chloride; In tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.202009699

Reference yield:

: 136918-14-4,85-41-6
phthalimide

: 88683-47-0
2-((4-nitrophenyl)thio)isoindoline-1,3-dione

Guidance literature:: Multi-step reaction with 3 steps

1.1: disulfur dichloride; triethylamine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere; Schlenk technique

2.1: sulfuryl dichloride; pyridine / dichloromethane / 48 h / 20 °C / Inert atmosphere; Schlenk technique

3.1: magnesium; lithium chloride; iodine / tetrahydrofuran / 2.5 h / 55 °C / Inert atmosphere; Schlenk technique

3.2: 1 h / 0 - 25 °C / Inert atmosphere; Schlenk technique

3.3: 0.83 h / 0 - 25 °C / Inert atmosphere; Schlenk technique

With pyridine; disulfur dichloride; sulfuryl dichloride; iodine; magnesium; triethylamine; lithium chloride; In tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.202009699