4-Nitrobenzenesulfonyl fluoride

Base Information

Chemical Name:4-Nitrobenzenesulfonyl fluoride
CAS No.:349-96-2
Molecular Formula:C6H4FNO4S
Molecular Weight:205.166
Hs Code.:29049090
European Community (EC) Number:631-547-9
DSSTox Substance ID:DTXSID00188458
Nikkaji Number:J208.801K
Wikidata:Q83060264
Mol file:349-96-2.mol

Synonyms:4-nitrobenzenesulfonyl fluoride;para-nitrobenzenesulfonyl fluoride;PNBSF

Suppliers and Price of 4-Nitrobenzenesulfonyl fluoride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
4-Nitrobenzenesulfonyl Fluoride
1g
$ 337.00

TRC
4-Nitrobenzenesulfonyl fluoride
1g
$ 115.00

SynQuest Laboratories
4-Nitrobenzenesulfonyl fluoride
1 g
$ 75.00

SynQuest Laboratories
4-Nitrobenzenesulfonyl fluoride
250 mg
$ 40.00

Sigma-Aldrich
4-Nitrobenzenesulfonyl fluoride 95%
1g
$ 114.00

Medical Isotopes, Inc.
4-Nitrobenzenesulfonyl fluoride
10 g
$ 1160.00

Matrix Scientific
4-Nitrobenzene-1-sulfonyl fluoride 95+%
25g
$ 285.00

Matrix Scientific
4-Nitrobenzene-1-sulfonyl fluoride 95+%
5g
$ 115.00

Crysdot
4-Nitrobenzene-1-sulfonylfluoride 97+%
10g
$ 104.00

Chemenu
4-Nitrobenzene-1-sulfonylfluoride 95+%
25g
$ 134.00

Total 38 raw suppliers

Chemical Property of 4-Nitrobenzenesulfonyl fluoride

Chemical Property:

Vapor Pressure:0.00151mmHg at 25°C
Melting Point:76-80 °C
Refractive Index:1.544
Boiling Point:305.1 °C at 760 mmHg
Flash Point:138.3 °C
PSA：88.34000
Density:1.554 g/cm³
LogP:2.85700
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:204.98450694
Heavy Atom Count:13
Complexity:283

Purity/Quality:

99% ^*data from raw suppliers

4-Nitrobenzenesulfonyl Fluoride ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C
Statements: 34
Safety Statements: 45-36/37/39-26-27

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1[N+](=O)[O-])S(=O)(=O)F
Uses 4-Nitrobenzenesulfonyl Fluoride is a protein modifying agent shown to be specific for tyrosine. Sulfonyl fluoride motif can be used as a connector for the assembly of -SO2- linked small molecules with proteins or nucleic acids. This new click chemistry approach through sulfates is a complimentary approach to using amides and phosphate groups as linkers.

Technology Process of 4-Nitrobenzenesulfonyl fluoride

There total 12 articles about 4-Nitrobenzenesulfonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 349-96-2
4-nitrobenzenesulfonyl fluoride

Guidance literature:: With potassium hydrogen difluoride; In water; acetonitrile; at 20 ℃; for 3h;

Reference yield: 96.0%

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 349-96-2
4-nitrobenzenesulfonyl fluoride

Guidance literature:: With potassium fluoride; 18-crown-6 ether; In water; toluene; at 55 ℃; for 8h; Large scale;
DOI:10.1021/acs.oprd.0c00080

Reference yield: 75.0%

: 3,3,7,7-tetrakis(difluoramino)octahydro-1,5-bis(4-nitrobenzenesulfonyl)-1,5-diazocine

: 349-96-2
4-nitrobenzenesulfonyl fluoride

: 3,3,7,7-tetrakis(difluoroamino)octahydro-1,5-dinitro-1,5-diazocine

Guidance literature:: 3,3,7,7-tetrakis(difluoramino)octahydro-1,5-bis(4-nitrobenzenesulfonyl)-1,5-diazocine; With trifluorormethanesulfonic acid; at 20 - 40 ℃; for 328h;

With nitric acid; at 0 - 20 ℃; for 1.08333h;

With sodium carbonate; In water; at 0 ℃; pH=5; Product distribution / selectivity;