N-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide

Base Information

Chemical Name:N-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide
CAS No.:88730-43-2
Molecular Formula:C9H8F3NO2
Molecular Weight:219.163
Hs Code.:
DSSTox Substance ID:DTXSID70523175
Wikidata:Q82389114

Synonyms:88730-43-2;N-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide;DTXSID70523175

Suppliers and Price of N-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:219.05071298
Heavy Atom Count:15
Complexity:234

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N(C1=CC=C(C=C1)C(F)(F)F)O

Technology Process of N-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide

There total 5 articles about N-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 102512-07-2
N-(4-(trifluoromethyl)phenyl)hydroxylamine

: 75-36-5
acetyl chloride

: 88730-43-2
N-Hydroxy-N-(4-trifluoromethyl-phenyl)-acetamide

Guidance literature:: With sodium hydrogencarbonate; In diethyl ether; water; at 0 ℃;
DOI:10.1021/ja00317a060

Reference yield:

: 402-54-0
p-nitrobenzotrifluoride

: 88730-43-2
N-Hydroxy-N-(4-trifluoromethyl-phenyl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: zinc dust, ammonium chloride / aq. ethanol

2: sodium bicarbonate / diethyl ether; H₂O / 0 °C

With ammonium chloride; sodium hydrogencarbonate; zinc; In diethyl ether; ethanol; water;
DOI:10.1021/ja00317a060