2-Aminophenyl diethylcarbamate

Base Information

Chemical Name:2-Aminophenyl diethylcarbamate
CAS No.:88733-57-7
Molecular Formula:C11H16N2O2
Molecular Weight:208.26
Hs Code.:
DSSTox Substance ID:DTXSID10521135
Wikidata:Q82385443

Synonyms:2-Aminophenyl diethylcarbamate;88733-57-7;DTXSID10521135

Suppliers and Price of 2-Aminophenyl diethylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Aminophenyl diethylcarbamate

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:208.121177757
Heavy Atom Count:15
Complexity:205

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)OC1=CC=CC=C1N

Technology Process of 2-Aminophenyl diethylcarbamate

There total 3 articles about 2-Aminophenyl diethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 905706-12-9
2-nitrosophenyl N,N-diethylcarbamate

: 88733-57-7
2-aminophenyl N,N-diethylcarbamate

Guidance literature:: With sodium tetrahydroborate; copper(l) chloride; In methanol; at 20 ℃; for 0.5h;
DOI:10.1021/ol0506563

Reference yield: 66.0%

: 65009-00-9
O-phenyl N,N-diethylcarbamate

: 88733-57-7
2-aminophenyl N,N-diethylcarbamate

Guidance literature:: O-phenyl N,N-diethylcarbamate; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 ℃; for 1h; Inert atmosphere;

With Triisopropyl borate; In tetrahydrofuran; pentane; at -78 - 20 ℃; Inert atmosphere;

With water; sodium hydroxide; hydroxylamine-O-sulfonic acid; In tetrahydrofuran; pentane; at 20 ℃; for 16h; regioselective reaction; Inert atmosphere;
DOI:10.1021/jo5025078

Reference yield:

: 85630-23-5
N,N-diethyl-O-(2-trimethylsilylphenyl)carbamate

: 88733-57-7
2-aminophenyl N,N-diethylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / NaNO₂; (CF₃CO)2O / acetonitrile / 10 h / -35 - 20 °C

2: 84 percent / CuCl; NaBH₄ / methanol / 0.5 h / 20 °C

With sodium tetrahydroborate; trifluoroacetic anhydride; copper(l) chloride; sodium nitrite; In methanol; acetonitrile;
DOI:10.1021/ol0506563