DIETHYL-CARBAMIC ACID PHENYL ESTER

Base Information

• Chemical Name: DIETHYL-CARBAMIC ACID PHENYL ESTER
• CAS No.: 65009-00-9
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Hs Code.: 2924299090
• Mol file: 65009-00-9.mol

Synonyms:Diethyl-carbamic acid phenyl ester;HMS1703L05;N,N-Diethylphenylcarbamate;Phenyl diethylcarbamate;

Chemical Property of DIETHYL-CARBAMIC ACID PHENYL ESTER

Chemical Property:

• Vapor Pressure: 0.00681mmHg at 25°C
• PSA: 29.54000
• LogP: 2.52720

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIETHYL-CARBAMIC ACID PHENYL ESTER

There total 24 articles about DIETHYL-CARBAMIC ACID PHENYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N,N-diethylcarbamyl chloride (88-10-8) + phenol (108-95-2,27073-41-2) → O-phenyl N,N-diethylcarbamate (65009-00-9)

Guidance literature:

phenol; With sodium hydride; In tetrahydrofuran; at 20 ℃;

N,N-diethylcarbamyl chloride; In tetrahydrofuran; at 20 ℃;

DOI:10.1055/s-2003-40822

Reference yield: 85.0%

carbon dioxide (124-38-9,18923-20-1) + diethylamine (109-89-7) + phenylboronic acid (98-80-6) → O-phenyl N,N-diethylcarbamate (65009-00-9)

Guidance literature:

With pyridine; copper(I) oxide; boron trifluoride diethyl etherate; oxygen; In dichloromethane; at 80 ℃; for 24h; under 30003 Torr; Solvent; Temperature; Time; Reagent/catalyst; Catalytic behavior; Autoclave;

DOI:10.1039/c6gc03465a

Reference yield: 84.0%

bis(phenyl) carbonate (102-09-0) + diethylamine (109-89-7) → O-phenyl N,N-diethylcarbamate (65009-00-9)

Guidance literature:

In tetrahydrofuran; water; at 20 ℃; for 8h;

DOI:10.1039/c7ob00872d

upstream raw materials:

N,N-diethylcarbamyl chloride

phenol

bis(phenyl) carbonate

diethylamine

Downstream raw materials:

N,N-diethyl-O-(2-trimethylsilylphenyl)carbamate

O-(2-N,N-diethylcarbamoyl)phenyl N,N-diethylcarbamate

O-(4-N,N-diethylcarbamoyl)phenyl N,N-diethylcarbamate

N,N-diethyl-1-carbamoyloxybenzene-2-carboxaldehyde

Refernces

• 1、 Dindarloo Inaloo, Iman,Majnooni, Sahar,Eslahi, Hassan,Esmaeilpour, Mohsen. "N -Arylation of (hetero)arylamines using aryl sulfamates and carbamates via C-O bond activation enabled by a reusable and durable nickel(0) catalyst". . p. 13266 - 13278. Retrieved 2020/10/07.
• 2、 G?bel, Dominik,Clamor, Nils,Lork, Enno,Nachtsheim, Boris J.. "Aerobic C(sp2)-H Hydroxylations of 2-Aryloxazolines: Fast Access to Excited-State Intramolecular Proton Transfer (ESIPT)-Based Luminophores". supporting information. p. 5373 - 5377. Retrieved 2019/06/07.