Technology Process of Tryptophan, N-benzoyl-4,5,6,7-tetrafluoro-, methyl ester
There total 12 articles about Tryptophan, N-benzoyl-4,5,6,7-tetrafluoro-, methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
methanol;
at 50 ℃;
for 17h;
under 7600 Torr;
DOI:10.1021/jo00280a014
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 94 percent / pyridine / 1.5 h / Heating
2: 86 percent / selenium dioxide / bis-(2-methoxy-ethyl) ether / 1.5 h / 160 °C
3: 91 percent / sodium acetate / tetrahydrofuran / 12 h / Heating
4: 91 percent / triethylamine / methanol / 1 h / Heating
5: 95 percent / H2 / 5percent Pd/C / methanol / 17 h / 50 °C / 7600 Torr
With
pyridine; selenium(IV) oxide; hydrogen; sodium acetate; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; diethylene glycol dimethyl ether;
DOI:10.1021/jo00280a014
- Guidance literature:
-
Multi-step reaction with 8 steps
1: CHCl3 / 0.5 h / Ambient temperature
2: LDA / tetrahydrofuran / Ambient temperature; 1.) -78 deg C, 2.) RT, 10 h
3: 1.) RhCl3*3H2O, 2.) conc. HCl / 1.) ethanol, reflux, 14 h, 2.) reflux, 20 min
4: 94 percent / pyridine / 1.5 h / Heating
5: 86 percent / selenium dioxide / bis-(2-methoxy-ethyl) ether / 1.5 h / 160 °C
6: 91 percent / sodium acetate / tetrahydrofuran / 12 h / Heating
7: 91 percent / triethylamine / methanol / 1 h / Heating
8: 95 percent / H2 / 5percent Pd/C / methanol / 17 h / 50 °C / 7600 Torr
With
pyridine; hydrogenchloride; rhodium(III) chloride; selenium(IV) oxide; hydrogen; sodium acetate; triethylamine; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; chloroform; diethylene glycol dimethyl ether;
DOI:10.1021/jo00280a014
