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Hippuric acid

Base Information Edit
  • Chemical Name:Hippuric acid
  • CAS No.:495-69-2
  • Deprecated CAS:140480-84-8,21251-67-2,66407-11-2,892119-18-5,892119-19-6,1361329-72-7,21251-67-2,66407-11-2,892119-18-5,892119-19-6
  • Molecular Formula:C9H9NO3
  • Molecular Weight:179.175
  • Hs Code.:29242990
  • European Community (EC) Number:207-806-3
  • NSC Number:9982
  • UNII:TE0865N2ET
  • DSSTox Substance ID:DTXSID9046073
  • Nikkaji Number:J1.562H
  • Wikipedia:Hippuric acid
  • Wikidata:Q412803
  • NCI Thesaurus Code:C87277
  • Metabolomics Workbench ID:37382
  • ChEMBL ID:CHEMBL461
  • Mol file:495-69-2.mol
Hippuric acid

Synonyms:Hippuricacid (8CI);2-(Benzoylamino)acetic acid;Acetic acid,(benzoylamino)-;Benzamidoacetic acid;Benzoyl Glycocoll;Benzoylglycine;N-Benzoylglycine;NSC 9982;Phenylcarbonylaminoacetic acid;Glycine,N-benzoyl-;

Suppliers and Price of Hippuric acid
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Hippuric acid 99+%
  • 100g
  • $ 162.00
  • TRC
  • Hippuric acid
  • 1g
  • $ 50.00
  • TRC
  • Hippuric acid
  • 500g
  • $ 95.00
  • TCI Chemical
  • Hippuric Acid >98.0%(T)
  • 500g
  • $ 68.00
  • TCI Chemical
  • Hippuric Acid >98.0%(T)
  • 25g
  • $ 15.00
  • TCI Chemical
  • Hippuric Acid >98.0%(T)
  • 100g
  • $ 28.00
  • SynQuest Laboratories
  • Hippuric acid
  • 25 g
  • $ 25.00
  • SynQuest Laboratories
  • Hippuric acid
  • 5 g
  • $ 20.00
  • SynQuest Laboratories
  • Hippuric acid
  • 100 g
  • $ 35.00
  • Sigma-Aldrich
  • Hippuric acid for synthesis. CAS 495-69-2, pH 2.5 - 3.5 (10 g/l, H O, 20 °C) (slurry)., for synthesis
  • 8206490100
  • $ 41.80
Total 150 raw suppliers
Chemical Property of Hippuric acid Edit
Chemical Property:
  • Appearance/Colour:White crystalline powder 
  • Vapor Pressure:2.06E-09mmHg at 25°C 
  • Melting Point:187-191 °C(lit.) 
  • Refractive Index:1.5600 (estimate) 
  • Boiling Point:464.125 °C at 760 mmHg 
  • PKA:3.62(at 25℃) 
  • Flash Point:234.495 °C 
  • PSA:66.40000 
  • Density:1.271 g/cm3 
  • LogP:0.89190 
  • Storage Temp.:Store at RT. 
  • Solubility.:3.26g/l 
  • Water Solubility.:Soluble in water. 
  • XLogP3:0.3
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:3
  • Exact Mass:179.058243149
  • Heavy Atom Count:13
  • Complexity:197
Purity/Quality:

99% *data from raw suppliers

Hippuric acid 99+% *data from reagent suppliers

Safty Information:
  • Pictogram(s): HarmfulXn,IrritantXi 
  • Hazard Codes:Xn,Xi 
  • Statements: 22-37/38-41-36/37/38 
  • Safety Statements: 26-39-36/37-22 
MSDS Files:

SDS file from LookChem

Useful:
  • Chemical Classes:Nitrogen Compounds -> Amino Carboxylic Acids
  • Canonical SMILES:C1=CC=C(C=C1)C(=O)NCC(=O)O
  • Recent NIPH Clinical Trials:A survey of the effect of exercise training in the change of kidney function for obese CKD patients
  • Uses The product is used for medicine, dyes intermediates and it is used for the production of fluorescent yellow H8GL, disperse fluorescent FFL and so on. N-Benzoylglycine also known as Hippuric Acid is the glycine conjugate of benzoic acid commonly found in ruminant urine. It is synthesized in the liver and its production is greatly increased following consuption of benzoic acid. In itself it does not have a direct biological function, however p-hydroxy-hippurica acid can be used as an inhibitor of Ca2+ ATPase. Hippuric acid is used as a intermediate for the manufacturing medicine and other organic compounds. Hippuric acid can be used to study cell biology, chemical biology, bioactive small molecules, amino acid derivatives, peptide synthesis, chemical synthesis and nutrition. Hippuric acid has been used to inform the metabolism and urinary excretion of procyanidins. Hippuric acid can be used to study cell biology, chemical biology, bioactive small molecules, amino acid derivatives, peptide synthesis, chemical synthesis and nutrition. Hippuric acid has been used to inform the metabolism and urinary excretion of procyanidins.
  • production method Benzoyl chloride reacts with the amino acid in sodium hydroxide solution, amido sodium benzene is obtained, then it is acidized with hydrochloric acid. The amino acid is dissolved in sodium hydroxide solution, at the same time drop? benzoyl chloride and sodium hydroxide solution? below 30 ℃? , the reaction solution is always alkaline. After finishing adding, stir for 30min. Then add? hydrochloric acid to pH 2, filter? crude, use water to recrystallize , hippuric acid is obtained. Consumption of raw materials fixed: amino acid (90%) 610kg/t, benzoyl chloride (60%) 1520kg/t, caustic soda (30%) 1960kg/t, hydrochloric acid (30%) 900kg/t.
Technology Process of Hippuric acid

There total 159 articles about Hippuric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; In sodium hydroxide;
Guidance literature:
With 2,4,6-tri-tert-butyl phenoxyl radical; In water; chlorobenzene; for 18h; Ambient temperature;
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