2-(2-(4-(3-Trifluoromethylphenyl)-1-piperazinyl)ethylamino)cyclopentanecarboxylic acid

Base Information

Chemical Name:2-(2-(4-(3-Trifluoromethylphenyl)-1-piperazinyl)ethylamino)cyclopentanecarboxylic acid
CAS No.:82608-10-4
Molecular Formula:C₁₉H₂₆F₃N₃O₂
Molecular Weight:385.43
Hs Code.:
DSSTox Substance ID:DTXSID401002817
Nikkaji Number:J77.932F

Synonyms:82608-10-4;2-(2-(4-(3-Trifluoromethylphenyl)-1-piperazinyl)ethylamino)cyclopentanecarboxylic acid;Cyclopentanecarboxylic acid, 2-((2-(4-(alpha,alpha,alpha-trifluoro-m-tolyl)-1-piperazinyl)ethyl)amino)-;C19H26F3N3O2;DTXSID401002817;C19-H26-F3-N3-O2;LS-57933;2-[2-[4-(3-Trifluoromethylphenyl)-1-piperazinyl]ethylamino]-1-cyclopentanecarboxylic acid;2-[(2-{4-[3-(Trifluoromethyl)phenyl]piperazin-1-yl}ethyl)amino]cyclopentane-1-carboxylic acid

Suppliers and Price of 2-(2-(4-(3-Trifluoromethylphenyl)-1-piperazinyl)ethylamino)cyclopentanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(2-(4-(3-Trifluoromethylphenyl)-1-piperazinyl)ethylamino)cyclopentanecarboxylic acid

Chemical Property:

Vapor Pressure:9.4E-12mmHg at 25°C
Boiling Point:522.7°Cat760mmHg
Flash Point:269.9°C
Density:1.3g/cm³
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:6
Exact Mass:385.19771157
Heavy Atom Count:27
Complexity:495

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C(C1)NCCN2CCN(CC2)C3=CC=CC(=C3)C(F)(F)F)C(=O)O

Technology Process of 2-(2-(4-(3-Trifluoromethylphenyl)-1-piperazinyl)ethylamino)cyclopentanecarboxylic acid

There total 4 articles about 2-(2-(4-(3-Trifluoromethylphenyl)-1-piperazinyl)ethylamino)cyclopentanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 82608-11-5
ethyl 2-<2-<4-(3-trifluoromethylphenyl)-1-piperaziny>ethylamino>cyclopentane carboxylate

: 82608-10-4
2-<2-<4-(3-trifluoromethylphenyl)-1-piperazinyl>ethylamino>cyclopentane carboxylic acid

Guidance literature:: With sodium hydroxide; for 3h; Heating;

Reference yield:

: 611-10-9
2-ethoxycarbonyl-1-cyclopentanone

: 82608-10-4
2-<2-<4-(3-trifluoromethylphenyl)-1-piperazinyl>ethylamino>cyclopentane carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / 48 h / Ambient temperature

2: 60 percent / 2 N HCl, NaBH₃CN / methanol / 24 h / 25 °C

3: 70 percent / 1 N NaOH / 3 h / Heating

With hydrogenchloride; sodium hydroxide; sodium cyanoborohydride; In methanol;

Reference yield:

: 91147-78-3
ethyl 2-<2-<4-(3-trifluoromethylphenyl)-1-piperazinyl>ethylamino>cyclopentene carboxylate

: 82608-10-4
2-<2-<4-(3-trifluoromethylphenyl)-1-piperazinyl>ethylamino>cyclopentane carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / 2 N HCl, NaBH₃CN / methanol / 24 h / 25 °C

2: 70 percent / 1 N NaOH / 3 h / Heating

With hydrogenchloride; sodium hydroxide; sodium cyanoborohydride; In methanol;