91147-78-3

Basic information

• Product Name: 1-Cyclopentene-1-carboxylic acid, 2-[[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]amino]-, ethyl ester
• CAS NO: 91147-78-3
• Molecular Formula: C21H28F3N3O2
• Molecular Weight: 411.467
• Mol File: 91147-78-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Cyclopentene-1-carboxylic acid, 2-[[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]amino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclopentene-1-carboxylic acid, 2-[[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]amino]-, ethyl ester(91147-78-3)
• EPA Substance Registry System: 1-Cyclopentene-1-carboxylic acid, 2-[[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]amino]-, ethyl ester(91147-78-3)

Safety Data

• Hazardous Substances Data: 91147-78-3(Hazardous Substances Data)

Upstream product

• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 27144-85-0 2-[4-(3-trifluoromethylphenyl)piperazin-1-yl]ethan-1-amine 

Downstream Products

• 82608-10-4 2-<2-<4-(3-trifluoromethylphenyl)-1-piperazinyl>ethylamino>cyclopentane carboxylic acid 
• 82608-11-5 ethyl 2-<2-<4-(3-trifluoromethylphenyl)-1-piperaziny>ethylamino>cyclopentane carboxylate 

Relevant articles and documents

Chemical and pharmacological studies of anorectic drugs with phenylpiperazinyl structure

Chemical and pharmacological properties of potent anorectic compounds with phenylpiperazinyl structure were studied. Among them, the three derivatives having the most interesting anorectic activity are product VI obtained by pharmacomodulation from amfepramone and the compounds IV and V, analogs of GABA. The derivative VI possesses an anorectic activity very similar to that of fenfluramine, namely: modification of feeding behaviour in treated rats, wasting away and crease of adipose tissue. The two other compounds and more particularly compound V seem to be effective even when treatment is over. Perhaps this is in relation with metabolic effects modifying the regulation of feeding behaviour in the central nervous system. In fact, these compounds have substituents able to interfere with GABA systems.