2-{[(1-Phenylethyl)sulfanyl]methyl}naphthalene

Base Information

• Chemical Name: 2-{[(1-Phenylethyl)sulfanyl]methyl}naphthalene
• CAS No.: 88766-14-7
• Molecular Formula: C19H18S
• Molecular Weight: 278.418
• DSSTox Substance ID: DTXSID70531477
• Mol file: 88766-14-7.mol

Synonyms:88766-14-7;2-{[(1-Phenylethyl)sulfanyl]methyl}naphthalene;DTXSID70531477

Chemical Property of 2-{[(1-Phenylethyl)sulfanyl]methyl}naphthalene

Chemical Property:

• XLogP3: 5.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 278.11292175
• Heavy Atom Count: 20
• Complexity: 282

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=CC=C1)SCC2=CC3=CC=CC=C3C=C2

Technology Process of 2-{[(1-Phenylethyl)sulfanyl]methyl}naphthalene

There total 3 articles about 2-{[(1-Phenylethyl)sulfanyl]methyl}naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-(mercaptomethyl)naphthalene (1076-67-1) + (1-chloroethyl)benzene (672-65-1) → (+/-)-2-naphthylmethyl 1-phenylethyl sulfide (88766-14-7)

Guidance literature:

With sodium ethanolate; In ethanol; for 3h; Heating;

DOI:10.1021/ja00318a037

Reference yield:

2-naphthylmethylisothiouronium bromide (88766-12-5) → (+/-)-2-naphthylmethyl 1-phenylethyl sulfide (88766-14-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / KOH / H₂O / Heating

2: 93 percent / NaOEt / ethanol / 3 h / Heating

With potassium hydroxide; sodium ethanolate; In ethanol; water;

DOI:10.1021/ja00318a037

Reference yield:

2-bromomethylnaphthyl bromide (939-26-4) → (+/-)-2-naphthylmethyl 1-phenylethyl sulfide (88766-14-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 88 percent / ethanol

2: 89 percent / KOH / H₂O / Heating

3: 93 percent / NaOEt / ethanol / 3 h / Heating

With potassium hydroxide; sodium ethanolate; In ethanol; water;

DOI:10.1021/ja00318a037

upstream raw materials:

2-(mercaptomethyl)naphthalene

(1-chloroethyl)benzene

2-naphthylmethylisothiouronium bromide

2-bromomethylnaphthyl bromide

Downstream raw materials:

(+/-)-2-naphthylmethyl 1-phenylethyl sulfone