Benzenamine, 4-[[6-[3-(dimethylamino)propoxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl] oxy]-3-fluoro-

Base Information

Chemical Name:Benzenamine, 4-[[6-[3-(dimethylamino)propoxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl] oxy]-3-fluoro-
CAS No.:888720-39-6
Molecular Formula:C₁₈H₂₂FN₅O₂
Molecular Weight:359.403
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzenamine, 4-[[6-[3-(dimethylamino)propoxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl] oxy]-3-fluoro-

Chemical Property:

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Technology Process of Benzenamine, 4-[[6-[3-(dimethylamino)propoxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl] oxy]-3-fluoro-

There total 1 articles about Benzenamine, 4-[[6-[3-(dimethylamino)propoxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl] oxy]-3-fluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 888720-38-5
C₁₈H₂₀FN₅O₄

: 888720-39-6
C₁₈H₂₂FN₅O₂

Guidance literature:: With ammonium chloride; zinc; In tetrahydrofuran; methanol; at 20 ℃; for 7h;
DOI:10.1016/j.bmcl.2008.01.121

Reference yield:

: 59-67-6
nicotinic acid

: 888720-39-6
C₁₈H₂₂FN₅O₂

: 888854-96-4
C₂₄H₂₅FN₆O₃

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 70 ℃; for 5h;
DOI:10.1016/j.bmcl.2008.01.121

Reference yield:

: 95262-10-5
3-((4-fluorophenyl)amino)-3-oxopropanoic acid

: 888720-39-6
C₁₈H₂₂FN₅O₂

: 888854-84-0
C₂₇H₂₈F₂N₆O₄

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1016/j.bmcl.2008.01.121