7,7-Dimethoxy-3-methyl-1-phenyl-3-azabicyclo[3.2.0]heptane

Base Information

Chemical Name:7,7-Dimethoxy-3-methyl-1-phenyl-3-azabicyclo[3.2.0]heptane
CAS No.:88905-25-3
Molecular Formula:C15H21NO2
Molecular Weight:247.337
Hs Code.:
ChEMBL ID:CHEMBL160532
DSSTox Substance ID:DTXSID90534061

Synonyms:88905-25-3;CHEMBL160532;DTXSID90534061;7,7-Dimethoxy-3-methyl-1-phenyl-3-azabicyclo[3.2.0]heptane

Suppliers and Price of 7,7-Dimethoxy-3-methyl-1-phenyl-3-azabicyclo[3.2.0]heptane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 7,7-Dimethoxy-3-methyl-1-phenyl-3-azabicyclo[3.2.0]heptane

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:247.157228913
Heavy Atom Count:18
Complexity:310

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CC2CC(C2(C1)C3=CC=CC=C3)(OC)OC

Technology Process of 7,7-Dimethoxy-3-methyl-1-phenyl-3-azabicyclo[3.2.0]heptane

There total 4 articles about 7,7-Dimethoxy-3-methyl-1-phenyl-3-azabicyclo[3.2.0]heptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 88905-21-9
7,7-Dimethoxy-3-methyl-1-phenyl-3-aza-bicyclo[3.2.0]heptane-2,4-dione

: 88905-25-3
7,7-Dimethoxy-3-methyl-1-phenyl-3-aza-bicyclo[3.2.0]heptane

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; 1.) RT, 0.5 h, 2.) reflux, 18 h;
DOI:10.1021/jm00371a012

Reference yield:

: 930-88-1
N-methylmaleimide

: 88905-25-3
7,7-Dimethoxy-3-methyl-1-phenyl-3-aza-bicyclo[3.2.0]heptane

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) 12 N aq. HCl, aq. NaNO₂, 2.) NaOAc, CuCl₂*2H₂O, 3.) 2,6-lutidine

2: 93 percent / K₂CO₃ / CH₂Cl₂ / Irradiation

3: 86 percent / NaAlH₂(OCH₂CH₂OCH₃)2 (Vitride-T) / toluene / 1.) RT, 0.5 h, 2.) reflux, 18 h

With 2,6-dimethylpyridine; hydrogenchloride; sodium acetate; potassium carbonate; sodium bis(2-methoxyethoxy)aluminium dihydride; sodium nitrite; In dichloromethane; toluene;
DOI:10.1021/jm00371a012

Reference yield:

: 54433-49-7
1-methyl- 3-phenyl-1H-pyrrole-2,5-dione

: 88905-25-3
7,7-Dimethoxy-3-methyl-1-phenyl-3-aza-bicyclo[3.2.0]heptane

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / K₂CO₃ / CH₂Cl₂ / Irradiation

2: 86 percent / NaAlH₂(OCH₂CH₂OCH₃)2 (Vitride-T) / toluene / 1.) RT, 0.5 h, 2.) reflux, 18 h

With potassium carbonate; sodium bis(2-methoxyethoxy)aluminium dihydride; In dichloromethane; toluene;
DOI:10.1021/jm00371a012