54433-49-7Relevant academic research and scientific papers
Palladium-catalyzed aerobic oxidative carbonylation of alkynes with amines: a general access to substituted maleimides
Yang, Ji,Liu, Jiawang,Jackstell, Ralf,Beller, Matthias
supporting information, p. 10710 - 10713 (2018/09/29)
A catalytic oxidative carbonylation reaction was developed for the synthesis of polysubstituted maleimides from alkynes and amines with air as a green oxidant. This novel transformation proceeds in the presence of palladium chloride without the need for expensive ligands or additives and has a broad substrate scope affording a variety of maleimides in good to high yields.
Pd(II)/bipyridine catalyzed conjugate addition of arylboronic acids to α,β-unsaturated amides
Ji, Jiamin,Yang, Zhenyu,Liu, Rui,Ni, Yuxin,Lin, Shaohui,Pan, Qinmin
, p. 2723 - 2726 (2016/06/09)
The Pd(II)/bipyridine-catalyzed conjugate addition of arylboronic acid to α,β-unsaturated amides was developed and optimized, and the reaction was proceeded smoothly in air. A series of arylboronic acid and α,β-unsaturated amide substrates were surveyed, and modest to excellent yields were given.
Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides
Manley-King, Clarina I.,Terre'Blanche, Gisella,Castagnoli Jr., Neal,Bergh, Jacobus J.,Petzer, Jacobus P.
experimental part, p. 3104 - 3110 (2009/09/05)
Based on a recent report that 1-methyl-3-phenylpyrrolyl analogues are moderately potent reversible inhibitors of the enzyme monoamine oxidase B (MAO-B), a series of structurally related N-methyl-2-phenylmaleimidyl analogues has been prepared and evaluated
