Chlornaltrexamine

Base Information

Chemical Name:Chlornaltrexamine
CAS No.:67025-94-9
Molecular Formula:C24H32Cl2N2O3
Molecular Weight:467.4285
Hs Code.:
DSSTox Substance ID:DTXSID90985877
Nikkaji Number:J21.397G
Wikipedia:Chlornaltrexamine
Wikidata:Q263676
ChEMBL ID:CHEMBL3228678
Mol file:67025-94-9.mol

Synonyms:6 beta-(N,N-bis(2-chloroethyl)amino)-17-(cyclopropylmethyl)-4,5 alpha-epoxy-3,14-dihydroxy morphinan;alpha-chlornaltrexamine;beta-chlornaltrexamine;beta-chloronaltrexamine;beta-CNA;chlornaltrexamine;chlornaltrexamine hydrochloride

Suppliers and Price of Chlornaltrexamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CHLORNALTREXAMINE 95.00%
5MG
$ 497.13

Total 3 raw suppliers

Chemical Property of Chlornaltrexamine

Chemical Property:

Vapor Pressure:3.94E-16mmHg at 25°C
Boiling Point:574.7°Cat760mmHg
Flash Point:301.4°C
PSA：56.17000
Density:1.42g/cm³
LogP:3.04240
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:466.1789983
Heavy Atom Count:31
Complexity:690

Purity/Quality:

99% ^*data from raw suppliers

CHLORNALTREXAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1CN2CCC34C5C(CCC3(C2CC6=C4C(=C(C=C6)O)O5)O)N(CCCl)CCCl
Isomeric SMILES:C1C[C@]2([C@H]3CC4=C5[C@@]2(CCN3CC6CC6)[C@H]([C@@H]1N(CCCl)CCCl)OC5=C(C=C4)O)O

Technology Process of Chlornaltrexamine

There total 2 articles about Chlornaltrexamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67025-95-0
6β-[bis-(2-hydroxy-ethyl)-amino]-17-cyclopropylmethyl-4,5α-epoxy-morphinane-3,14-diol

: 67025-94-9
β-chlornaltrexamine

Guidance literature:: With tetrachloromethane; triphenylphosphine; In N,N-dimethyl-formamide;
DOI:10.1021/jm00205a002

Reference yield:

: 67025-97-2
6β-naltrexamine

: 67025-94-9
β-chlornaltrexamine

Guidance literature:: Multi-step reaction with 2 steps

2: Ph₃P, CCl₄ / dimethylformamide

With tetrachloromethane; triphenylphosphine; In N,N-dimethyl-formamide;
DOI:10.1021/jm00205a002