2-amino-1-(2,4-dichlorophenyl)ethan-1-ol

Base Information

Chemical Name:2-amino-1-(2,4-dichlorophenyl)ethan-1-ol
CAS No.:88965-93-9
Molecular Formula:C₈H₉Cl₂NO
Molecular Weight:206.072
Hs Code.:
Mol file:88965-93-9.mol

Synonyms:(±)-2-(2,4-Dichlorophenyl)-2-hydroxyethylamine;2-Amino-1-(2,4-dichlorophenyl)ethanol HCl;

Suppliers and Price of 2-amino-1-(2,4-dichlorophenyl)ethan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(±)-2-(2,4-Dichlorophenyl)-2-hydroxyethylamine
25mg
$ 120.00

AK Scientific
2-Amino-1-(2,4-dichlorophenyl)ethan-1-ol
10g
$ 1836.00

AK Scientific
2-Amino-1-(2,4-dichlorophenyl)ethan-1-ol
5g
$ 1269.00

AK Scientific
2-Amino-1-(2,4-dichlorophenyl)ethan-1-ol
1g
$ 503.00

Acrotein
2-Amino-1-(2,4-dichlorophenyl)ethanolHCl 97%
1g
$ 293.33

Total 11 raw suppliers

Chemical Property of 2-amino-1-(2,4-dichlorophenyl)ethan-1-ol

Chemical Property:

Boiling Point:354.1±37.0 °C(Predicted)
PKA:11.28±0.35(Predicted)
PSA：46.25000
Density:1.391±0.06 g/cm3(Predicted)
LogP:2.68580
Solubility.:Methanol

Purity/Quality:

99% ^*data from raw suppliers

(±)-2-(2,4-Dichlorophenyl)-2-hydroxyethylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (±)-2-(2,4-Dichlorophenyl)-2-hydroxyethylamine is an intermediate in the synthesis of Aminoazabenzimidazoles, a novel class of orally active antimalarial agent.

Technology Process of 2-amino-1-(2,4-dichlorophenyl)ethan-1-ol

There total 1 articles about 2-amino-1-(2,4-dichlorophenyl)ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 10324-56-8
2-(2,4-dichlorophenyl)-2-hydroxyacetonitrile

: 88965-93-9
2-amino-1-(2,4-dichlorophenyl)ethanol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; Heating;
DOI:10.1021/jm00339a011

Reference yield:

: 88965-93-9
2-amino-1-(2,4-dichlorophenyl)ethanol

: 1616406-43-9
2-((3-aminopyridin-4-yl)amino)-1-(2,4-dichlorophenyl)ethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere

1.2: 2 h / 20 °C / Inert atmosphere

2.1: tin(II) chloride dihdyrate / ethanol / 3 h / 90 °C / Reflux; Inert atmosphere

2.2: Inert atmosphere

With tin(II) chloride dihdyrate; sodium hydride; In tetrahydrofuran; ethanol;
DOI:10.1021/jm500535j

Reference yield:

: 88965-93-9
2-amino-1-(2,4-dichlorophenyl)ethanol

: 1616405-95-8
2-(2-amino-1H-imidazo[4,5-c]pyridin-1-yl)-1-(2,4-dichlorophenyl)ethanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere

1.2: 2 h / 20 °C / Inert atmosphere

2.1: tin(II) chloride dihdyrate / ethanol / 3 h / 90 °C / Reflux; Inert atmosphere

2.2: Inert atmosphere

3.1: methanol; water / 90 °C / Inert atmosphere

With tin(II) chloride dihdyrate; sodium hydride; In tetrahydrofuran; methanol; ethanol; water;
DOI:10.1021/jm500535j