Benzeneacetic acid, 2-(2-thiazolyloxy)-

Base Information

Chemical Name:Benzeneacetic acid, 2-(2-thiazolyloxy)-
CAS No.:88975-98-8
Molecular Formula:C₁₁H₉NO₃S
Molecular Weight:235.263
Hs Code.:

Synonyms:

Suppliers and Price of Benzeneacetic acid, 2-(2-thiazolyloxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Benzeneacetic acid, 2-(2-thiazolyloxy)-

Chemical Property:

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzeneacetic acid, 2-(2-thiazolyloxy)-

There total 7 articles about Benzeneacetic acid, 2-(2-thiazolyloxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [2-(Thiazol-2-yloxy)-phenyl]-acetic acid methyl ester

: 88975-98-8
[2-(Thiazol-2-yloxy)-phenyl]-acetic acid

Guidance literature:: With sodium hydroxide; In methanol; at 40 ℃; for 3h; Yield given;
DOI:10.1248/cpb.31.3424

Reference yield:

: 610-66-2
2-nitro-benzeneacetonitrile

: 88975-98-8
[2-(Thiazol-2-yloxy)-phenyl]-acetic acid

Guidance literature:: Multi-step reaction with 7 steps

1: 79 percent / H₂ / Pd-C

2: 1.) NaNO₂, H₂O/7.3percent H₂SO₄ / 1.) 0 deg C, 2 h; 2.) toluene, reflux, 15 min

3: triethylamine / diethyl ether / 2 h / -10 °C

4: H₂S/triethylamine / diethyl ether / 0.83 h / Ambient temperature

5: p-toluenesulfonic acid / acetic acid / 1.5 h / 90 - 95 °C

6: gaseous HCl / 3 h / 55 °C

7: 5percent aq NaOH / methanol / 3 h / 40 °C

With hydrogenchloride; sodium hydroxide; sulfuric acid; hydrogen sulfide; water; hydrogen; toluene-4-sulfonic acid; triethylamine; sodium nitrite; palladium on activated charcoal; In methanol; diethyl ether; acetic acid;
DOI:10.1248/cpb.31.3424

Reference yield:

: 14714-50-2
2-hydroxybenzyl cyanide

: 88975-98-8
[2-(Thiazol-2-yloxy)-phenyl]-acetic acid

Guidance literature:: Multi-step reaction with 5 steps

1: triethylamine / diethyl ether / 2 h / -10 °C

2: H₂S/triethylamine / diethyl ether / 0.83 h / Ambient temperature

3: p-toluenesulfonic acid / acetic acid / 1.5 h / 90 - 95 °C

4: gaseous HCl / 3 h / 55 °C

5: 5percent aq NaOH / methanol / 3 h / 40 °C

With hydrogenchloride; sodium hydroxide; hydrogen sulfide; toluene-4-sulfonic acid; triethylamine; In methanol; diethyl ether; acetic acid;
DOI:10.1248/cpb.31.3424