6-Benzyl-4-ethenylidene-6-azabicyclo[3.2.1]octan-7-one

Base Information

Chemical Name:6-Benzyl-4-ethenylidene-6-azabicyclo[3.2.1]octan-7-one
CAS No.:88996-10-5
Molecular Formula:C16H17NO
Molecular Weight:239.317
Hs Code.:
DSSTox Substance ID:DTXSID60532559

Synonyms:88996-10-5;6-Benzyl-4-ethenylidene-6-azabicyclo[3.2.1]octan-7-one;DTXSID60532559

Suppliers and Price of 6-Benzyl-4-ethenylidene-6-azabicyclo[3.2.1]octan-7-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6-Benzyl-4-ethenylidene-6-azabicyclo[3.2.1]octan-7-one

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:239.131014166
Heavy Atom Count:18
Complexity:388

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=C=C1CCC2CC1N(C2=O)CC3=CC=CC=C3

Technology Process of 6-Benzyl-4-ethenylidene-6-azabicyclo[3.2.1]octan-7-one

There total 10 articles about 6-Benzyl-4-ethenylidene-6-azabicyclo[3.2.1]octan-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 88996-04-7
1-Benzyl-5-ethoxy-3-(5-trimethylsilanyl-pent-3-ynyl)-pyrrolidin-2-one

: 88996-10-5,108634-66-8
6-benzyl-4-vinylidene-6-azabicyclo<3.2.1>octan-7-one

Guidance literature:: In formic acid; for 0.5h; Ambient temperature;

Reference yield: 88.0%

: 88996-04-7
1-Benzyl-5-ethoxy-3-(5-trimethylsilanyl-pent-3-ynyl)-pyrrolidin-2-one

: 88996-10-5
6-Benzyl-4-vinylidene-6-aza-bicyclo[3.2.1]octan-7-one

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 1h; Ambient temperature;
DOI:10.1021/jo00180a046

Reference yield:

: 2142-06-5
1-(phenylmethyl)-2,5-pyrrolidinedione

: 88996-10-5
6-Benzyl-4-vinylidene-6-aza-bicyclo[3.2.1]octan-7-one

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / NaBH₄, acid

2: 1.) LDA / 1.) THF, -78 deg C, 2.) -78 deg C, 30 min, 3.) -78 -> 0 deg C, 2h

3: 88 percent / CF₃CO₂H / CH₂Cl₂ / 1 h / Ambient temperature

With sodium tetrahydroborate; trifluoroacetic acid; lithium diisopropyl amide; In dichloromethane;
DOI:10.1021/jo00180a046