Ethyl 3-amino-4-ethenylcyclohexane-1-carboxylate

Base Information

Chemical Name:Ethyl 3-amino-4-ethenylcyclohexane-1-carboxylate
CAS No.:88996-21-8
Molecular Formula:C₁₁H₁₉NO₂
Molecular Weight:197.277
Hs Code.:
DSSTox Substance ID:DTXSID10532564

Synonyms:88996-21-8;Ethyl 3-amino-4-ethenylcyclohexane-1-carboxylate;DTXSID10532564

Suppliers and Price of Ethyl 3-amino-4-ethenylcyclohexane-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ethyl 3-amino-4-ethenylcyclohexane-1-carboxylate

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:197.141578849
Heavy Atom Count:14
Complexity:215

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1CCC(C(C1)N)C=C

Technology Process of Ethyl 3-amino-4-ethenylcyclohexane-1-carboxylate

There total 8 articles about Ethyl 3-amino-4-ethenylcyclohexane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 64-17-5
ethanol

: 121823-76-5
4-vinyl-6-azabicyclo<3.2.1>octan-7-one

: 88996-21-8,121823-77-6,121823-84-5
rel-(1R,2R,4R)-2-amino-4-carbethoxy-1-vinyl-cyclohexane

Guidance literature:: With hydrogenchloride; Heating;
DOI:10.1021/jo00180a046

Reference yield:

: 121823-52-7,121823-57-2
1-benzyl-5-methoxy-3-<5-(trimethylsilyl)-3-pentynyl>-2-pyrrolidinnone

: 88996-21-8,121823-77-6,121823-84-5
rel-(1R,2R,4R)-2-amino-4-carbethoxy-1-vinyl-cyclohexane

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / H₂, NaBH₄, Ni(OAc)2*4H₂O, 0.1M NaOH, 1,2-diaminoethane / ethanol / 17 h

2: formic acid / 0.5 h / Ambient temperature

3: 81 percent / sodium, liq. ammonia / 1 h / -33 °C

4: 88 percent / HCl / 19 h / Heating

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; formic acid; ammonia; hydrogen; sodium; nickel diacetate; ethylenediamine; In ethanol;
DOI:10.1016/S0040-4020(01)90113-9

Reference yield:

: 88996-11-6,88996-12-7
(1R,4R,5R)-6-Benzyl-4-vinyl-6-aza-bicyclo[3.2.1]octan-7-one

: 88996-21-8,121823-77-6,121823-84-5
rel-(1R,2R,4R)-2-amino-4-carbethoxy-1-vinyl-cyclohexane

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / sodium, liq. ammonia / 1 h / -33 °C

2: 88 percent / HCl / 19 h / Heating

With hydrogenchloride; ammonia; sodium;
DOI:10.1016/S0040-4020(01)90113-9