Ethyl [2-(4-chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetate

Base Information

Chemical Name:Ethyl [2-(4-chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetate
CAS No.:89006-89-3
Molecular Formula:C18H22ClNO3
Molecular Weight:335.831
Hs Code.:
DSSTox Substance ID:DTXSID80542039
Wikidata:Q82418552

Synonyms:SCHEMBL11004559;DTXSID80542039;DKSWMQPYQHTWBL-UHFFFAOYSA-N;Ethyl [2-(4-chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetate;ethyl 2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetate

Suppliers and Price of Ethyl [2-(4-chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl [2-(4-chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetate

Chemical Property:

XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:335.1288213
Heavy Atom Count:23
Complexity:358

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC1=C(N=C(O1)C2=CC=C(C=C2)Cl)CC(=O)OCC

Technology Process of Ethyl [2-(4-chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetate

There total 5 articles about Ethyl [2-(4-chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.2%

: 89006-89-3
ethyl 2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetate

Guidance literature:

Reference yield: 84.0%

: 89006-88-2
ethyl 3-(4-chlorobenzoylamino)-3-n-caproylpropionate

: 89006-89-3
ethyl 2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetate

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-formamide; 0 deg C then rt.;
DOI:10.1248/cpb.36.4435

Reference yield:

: 89007-04-5
aminomethyl n-pentyl ketone hydrochloride

: 89006-89-3
ethyl 2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / sodium bicarbonate / ethyl acetate; H₂O / Ambient temperature

2: 56 percent / 61 percent sodium hydride in paraffine / dimethylformamide / -50 deg C, up to 10 deg C

3: 84 percent / phosphoryl chloride / dimethylformamide / 0 deg C then rt.

With sodium hydride; sodium hydrogencarbonate; trichlorophosphate; In water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.36.4435