[2-(4-Chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetic acid

Base Information

Chemical Name:[2-(4-Chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetic acid
CAS No.:89006-95-1
Molecular Formula:C16H18ClNO3
Molecular Weight:307.777
Hs Code.:
DSSTox Substance ID:DTXSID90542040
Wikidata:Q82418553

Synonyms:89006-95-1;2-(2-(4-Chlorophenyl)-5-pentyloxazol-4-yl)acetic acid;SCHEMBL11003486;DTXSID90542040;SEBUBKBGKGHTTQ-UHFFFAOYSA-N;[2-(4-Chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetic acid;2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetic acid

Suppliers and Price of [2-(4-Chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of [2-(4-Chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetic acid

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:307.0975211
Heavy Atom Count:21
Complexity:332

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC1=C(N=C(O1)C2=CC=C(C=C2)Cl)CC(=O)O

Technology Process of [2-(4-Chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetic acid

There total 5 articles about [2-(4-Chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 89006-89-3
ethyl 2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetate

: 89006-95-1
2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetic acid

Guidance literature:: With potassium hydroxide; In methanol; water; Ambient temperature;
DOI:10.1248/cpb.36.4435

Reference yield:

: 89007-04-5
aminomethyl n-pentyl ketone hydrochloride

: 89006-95-1
2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / sodium bicarbonate / ethyl acetate; H₂O / Ambient temperature

2: 56 percent / 61 percent sodium hydride in paraffine / dimethylformamide / -50 deg C, up to 10 deg C

3: 84 percent / phosphoryl chloride / dimethylformamide / 0 deg C then rt.

4: 87 percent / potassium hydroxide / methanol; H₂O / Ambient temperature

With potassium hydroxide; sodium hydride; sodium hydrogencarbonate; trichlorophosphate; In methanol; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.36.4435

Reference yield:

: 122-01-0
4-chloro-benzoyl chloride

: 89006-95-1
2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / sodium bicarbonate / ethyl acetate; H₂O / Ambient temperature

2: 56 percent / 61 percent sodium hydride in paraffine / dimethylformamide / -50 deg C, up to 10 deg C

3: 84 percent / phosphoryl chloride / dimethylformamide / 0 deg C then rt.

4: 87 percent / potassium hydroxide / methanol; H₂O / Ambient temperature

With potassium hydroxide; sodium hydride; sodium hydrogencarbonate; trichlorophosphate; In methanol; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.36.4435