2-Hydroxy-4-iodobenzoyl chloride

Base Information

Chemical Name:2-Hydroxy-4-iodobenzoyl chloride
CAS No.:89011-19-8
Molecular Formula:C7H4ClIO2
Molecular Weight:282.465
Hs Code.:
DSSTox Substance ID:DTXSID80522179
Wikidata:Q82387226

Synonyms:2-Hydroxy-4-iodobenzoyl chloride;89011-19-8;SCHEMBL15270445;DTXSID80522179;OOHRYZXMTCZOBJ-UHFFFAOYSA-N;2-hydroxy-4-iodo-benzoyl chloride

Suppliers and Price of 2-Hydroxy-4-iodobenzoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Hydroxy-4-iodobenzoyl chloride

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:281.89445
Heavy Atom Count:11
Complexity:163

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1I)O)C(=O)Cl

Technology Process of 2-Hydroxy-4-iodobenzoyl chloride

There total 3 articles about 2-Hydroxy-4-iodobenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 16870-28-3
4-iodosalicylic acid

: 89011-19-8
2-hydroxy-4-iodobenzoyl chloride

Guidance literature:: With thionyl chloride; for 2h; Heating;
DOI:10.1021/jm970121i

Reference yield:

: 65-49-6
4-Aminosalicylic acid

: 89011-19-8
2-hydroxy-4-iodobenzoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) aq. NaNO₂, aq. H₂SO₄, 2.) KI / 1.) 5 deg C, 2.) from 75 deg C to 95 deg C, 20 min

2: 84 percent / SOCl₂ / 2 h / Heating

With thionyl chloride; sulfuric acid; potassium iodide; sodium nitrite;
DOI:10.1021/jm970121i