16870-28-3

Basic information

• Product Name: 2-HYDROXY-4-IODOBENZOIC ACID
• Synonyms: 2-HYDROXY-4-IODOBENZOIC ACID;4-iodosalicylic acid;2-Hydroxy-4-iodobenzoic acid 97%
• CAS NO: 16870-28-3
• Molecular Formula: C₇H₅IO₃
• Molecular Weight: 264.02
• Product Categories: Benzoic acid;Acids & Esters;Iodine Compounds;Phenols
• Mol File: 16870-28-3.mol
• Article Data: 17

Chemical Properties

• Melting Point: 230°C
• Boiling Point: 362.569 °C at 760 mmHg
• Flash Point: 173.076 °C
• Appearance: /
• Density: 2.156 g/cm³
• Vapor Pressure: 6.84E-06mmHg at 25°C
• Refractive Index: 1.712
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.70±0.10(Predicted)
• CAS DataBase Reference: 2-HYDROXY-4-IODOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-4-IODOBENZOIC ACID(16870-28-3)
• EPA Substance Registry System: 2-HYDROXY-4-IODOBENZOIC ACID(16870-28-3)

Safety Data

• Hazard Codes: C,T
• Statements: 25-41
• Safety Statements: 26-39-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 1
• HazardClass: IRRITANT
• Hazardous Substances Data: 16870-28-3(Hazardous Substances Data)

Usage

General Description

2-Hydroxy-4-iodobenzoic acid is a chemical compound that belongs to the class of aromatic carboxylic acids. It is a derivative of benzoic acid with a hydroxyl group and an iodine atom attached to the benzene ring. 2-HYDROXY-4-IODOBENZOIC ACID is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds. It is also used as an intermediate in the production of dyes, pigments, and other fine chemicals. The presence of the hydroxyl and iodine groups in 2-hydroxy-4-iodobenzoic acid makes it a valuable chemical for use in a wide range of applications. Note: This information is for informational purposes only and should not be considered as a direct source for making medical decisions. Always consult with a professional for any medical advice.

InChI:InChI=1/C7H5IO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,(H,10,11)

Upstream product

• 65-49-6 4-Aminosalicylic acid 
• 69-72-7 salicylic acid 
• 18179-39-0 methyl 4-iodosalicylate 
• 6059-17-2 ethyl 4-amino-2-hydroxybenzoate 
• 38170-02-4 4-iodosalicylaldehyde 
• 730977-57-8 ethyl 2-hydroxy-4-iodobenzoate 
• 89942-34-7 2-methoxy-4-iodobenzoic acid 
• 78987-51-6 2-hydroxy-4-nitro-benzoic acid ethyl ester 
• 626-02-8 3-Iodophenol 

Downstream Products

• 89942-34-7 2-methoxy-4-iodobenzoic acid 
• 170282-08-3 benzyl 2-(benzyloxy)-4-iodobenzoate 
• 4482-27-3 3-hydroxy-[1,1'-biphenyl]-4-carboxylic acid 
• 730977-57-8 ethyl 2-hydroxy-4-iodobenzoate 

Relevant articles and documents

Preparation method of p-vinylsalicylic acid

The invention discloses a p-vinylsalicylic acid preparation method, which comprises: (1) carrying out a diazotization reaction on p-aminosalicylic acid and nitrous acid in water to generate a diazotization intermediate, and adding a metal iodide to carry

Acetylene Bridged Linkers and Metal-Organic Frameworks (MOFs) Produced Thereof

Described are acetylene bridged linkers, metal-organic frameworks produced thereof, processes for producing the linkers and the metal-organic frameworks, and the use of the metal-organic frameworks. The metal-organic frameworks possess an enhanced ability to adsorb and desorb high amounts of gases, in particular methane or hydrogen. The metal-organic frameworks have a high porosity and, thus, a high inner surface.

Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists

A series of acrylic acids and their structurally related compounds were evaluated for their binding affinity to four EP receptor subtypes (EP1-4). Starting from the initial hit 3, which was discovered in our in-house library, compounds 4 and 5 were identified as new chemical leads as candidates for further optimization towards a selective EP3 receptor antagonist. The identification process of these compounds and their pharmacokinetic profiles are presented.