16870-28-3

Usage

Uses

Used in Organic Synthesis:
2-Hydroxy-4-iodobenzoic acid is used as a building block in organic synthesis for the creation of various biologically active compounds. Its presence of both hydroxyl and iodine groups allows for versatile chemical reactions, making it a key component in the synthesis of pharmaceuticals and other organic compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, 2-hydroxy-4-iodobenzoic acid serves as an intermediate for the development of new drugs. Its unique chemical properties enable the design and synthesis of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Dye and Pigment Production:
2-Hydroxy-4-iodobenzoic acid is also utilized as an intermediate in the production of dyes and pigments. Its chemical structure contributes to the color and stability of these products, making it an essential component in the manufacturing process of various colorants used in different industries.
Used in Fine Chemicals Industry:
2-HYDROXY-4-IODOBENZOIC ACID finds application in the fine chemicals industry, where it is used as an intermediate for the synthesis of specialty chemicals. These fine chemicals have a wide range of uses, including in the production of fragrances, flavorings, and other high-value chemical products.

InChI:InChI=1/C7H5IO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,(H,10,11)

Upstream product

• 65-49-6 4-Aminosalicylic acid 
• 69-72-7 salicylic acid 
• 78987-51-6 2-hydroxy-4-nitro-benzoic acid ethyl ester 
• 6059-17-2 ethyl 4-amino-2-hydroxybenzoate 
• 38170-02-4 4-iodosalicylaldehyde 
• 730977-57-8 ethyl 2-hydroxy-4-iodobenzoate 
• 89942-34-7 2-methoxy-4-iodobenzoic acid 
• 18179-39-0 methyl 4-iodosalicylate 
• 626-02-8 3-Iodophenol 

Downstream Products

• 89942-34-7 2-methoxy-4-iodobenzoic acid 
• 18179-39-0 methyl 4-iodosalicylate 
• 730977-57-8 ethyl 2-hydroxy-4-iodobenzoate 
• 71534-98-0 4-ethenyl-2-hydroxybenzoic acid 

Relevant academic research and scientific papers

Preparation method of p-vinylsalicylic acid

The invention discloses a p-vinylsalicylic acid preparation method, which comprises: (1) carrying out a diazotization reaction on p-aminosalicylic acid and nitrous acid in water to generate a diazotization intermediate, and adding a metal iodide to carry

LANTHANIDE CLUSTERS AND METHODS OF USE THEREOF

The present invention is directed to multinuclear lanthanides chiral clusters, based on phenyl-oxazoline-amide (POxA) ligands, and to methods of use thereof. The chiral clusters of this invention are highly fluorescent with high stability.

Acetylene Bridged Linkers and Metal-Organic Frameworks (MOFs) Produced Thereof

Described are acetylene bridged linkers, metal-organic frameworks produced thereof, processes for producing the linkers and the metal-organic frameworks, and the use of the metal-organic frameworks. The metal-organic frameworks possess an enhanced ability to adsorb and desorb high amounts of gases, in particular methane or hydrogen. The metal-organic frameworks have a high porosity and, thus, a high inner surface.

ACETYLENE BRIDGED LINKERS AND METAL-ORGANIC FRAMEWORKS (MOFS) PRODUCED THEREOF

The present invention relates to acetylene bridged linkers, metal-organic frameworks produced thereof, processes for producing the linkers and the MOFs and their use.

Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists

A series of acrylic acids and their structurally related compounds were evaluated for their binding affinity to four EP receptor subtypes (EP1-4). Starting from the initial hit 3, which was discovered in our in-house library, compounds 4 and 5 were identified as new chemical leads as candidates for further optimization towards a selective EP3 receptor antagonist. The identification process of these compounds and their pharmacokinetic profiles are presented.

Iodination of aryl amines in a water-paste form via stable aryl diazonium tosylates

The diazotization of aryl amines at room temperature in paste form with NaNO2, p-TsOH and a small amount of water, followed by treatment with KI provides a new, simple, and effective route for the preparation of various aryl iodides. The water-paste and strong acid-free reaction conditions are environmentally friendly and compatible with acid-sensitive functional groups.

Compounds and Compositions as Tpo Mimetics

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TPO activity, particularly disea

FUSED HETEROCYCLIC COMPOUND AND USE THEREOF

The present invention relates to wherein each symbol is as defined in the specification. The compound has a superior mineral corticoidreceptorantagonistic action and is useful as an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like, a compound having a fused heterocycle, or a prodrug thereof, or a salt thereof; and an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like.

METHODS FOR TREATING HEPATITIS C

In accordance with the present invention, compounds that inhibit viral replication, preferably Hepatitis C Virus (HCV) replication, have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the treatment