Benzamide, 4-[2-(4-pentylcyclohexyl)ethyl]-, trans-

Base Information

• Chemical Name: Benzamide, 4-[2-(4-pentylcyclohexyl)ethyl]-, trans-
• CAS No.: 89013-06-9
• Molecular Formula: C₂₀H₃₁NO
• Molecular Weight: 301.472
• Mol file: 89013-06-9.mol

Synonyms:

Chemical Property of Benzamide, 4-[2-(4-pentylcyclohexyl)ethyl]-, trans-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzamide, 4-[2-(4-pentylcyclohexyl)ethyl]-, trans-

There total 10 articles about Benzamide, 4-[2-(4-pentylcyclohexyl)ethyl]-, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

4-[2-(4-Pentyl-cyclohexyl)-ethyl]-benzoyl chloride (89013-10-5) → 4-[2-(4-Pentyl-cyclohexyl)-ethyl]-benzamide (89013-06-9)

Guidance literature:

With ammonium hydroxide;

Reference yield:

4-trans-pentylcyclohexane-1-carboxylic acid (38289-29-1,38792-89-1,67589-84-8) → 4-[2-(4-Pentyl-cyclohexyl)-ethyl]-benzamide (89013-06-9)

Guidance literature:

Multi-step reaction with 10 steps

1: 100 percent / SOCl₂

2: 91 percent / LiAlH₄ / diethyl ether

3: 76 percent / HBr, aq/H₂SO₄

4: 93 percent / dimethylsulfoxide

5: 78 percent / H₂SO₄ / acetic acid

6: 100 percent / SOCl₂

7: 75 percent / Friedel Crafts reaction

8: 69 percent / Huang-Minlon reduction

9: 73 percent / AlCl₃ / CH₂Cl₂

10: 65 percent / aq. NH₃

With ammonium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; thionyl chloride; sulfuric acid; hydrogen bromide; In diethyl ether; dichloromethane; acetic acid; dimethyl sulfoxide;

Reference yield:

trans-4-pentylcyclohexanecarboxamide (71458-08-7) → 4-[2-(4-Pentyl-cyclohexyl)-ethyl]-benzamide (89013-06-9)

Guidance literature:

Multi-step reaction with 8 steps

1: 76 percent / HBr, aq/H₂SO₄

2: 93 percent / dimethylsulfoxide

3: 78 percent / H₂SO₄ / acetic acid

4: 100 percent / SOCl₂

5: 75 percent / Friedel Crafts reaction

6: 69 percent / Huang-Minlon reduction

7: 73 percent / AlCl₃ / CH₂Cl₂

8: 65 percent / aq. NH₃

With ammonium hydroxide; aluminium trichloride; thionyl chloride; sulfuric acid; hydrogen bromide; In dichloromethane; acetic acid; dimethyl sulfoxide;

upstream raw materials:

4-[2-(4-Pentyl-cyclohexyl)-ethyl]-benzoyl chloride

4-trans-pentylcyclohexane-1-carboxylic acid

trans-4-pentylcyclohexanecarboxamide

trans-4-bromomethyl-1-n-pentylcyclohexane

Downstream raw materials:

p-[2-(trans-4-pentylcyclohexyl)ethyl]benzonitrile