(1-Benzyl-4-oxo-piperidin-3-yl)-acetic acid ethyl ester

Base Information

Chemical Name:(1-Benzyl-4-oxo-piperidin-3-yl)-acetic acid ethyl ester
CAS No.:6947-75-7
Molecular Formula:C16H21 N O3
Molecular Weight:275.348
Hs Code.:2933399090
NSC Number:56141
Mol file:6947-75-7.mol

Synonyms:6947-75-7;(1-Benzyl-4-oxo-piperidin-3-yl)-acetic acid ethyl ester;ethyl 2-(1-benzyl-4-oxopiperidin-3-yl)acetate;NSC56141;Ethyl (1-benzyl-4-oxo-3-piperidinyl)acetate;NSC 56141;NCIOpen2_002461;SCHEMBL10932090;MFCD28404790;NSC-56141;AS-40192;ethyl 2-(1-benzyl-4-oxo-3-piperidyl)acetate;ethyl2-(1-benzyl-4-oxopiperidin-3-yl)acetate;A840968;2-[4-oxo-1-(phenylmethyl)-3-piperidinyl]acetic acid ethyl ester;ethyl 2-[4-oxidanylidene-1-(phenylmethyl)piperidin-3-yl]ethanoate

Suppliers and Price of (1-Benzyl-4-oxo-piperidin-3-yl)-acetic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl2-(1-benzyl-4-oxopiperidin-3-yl)acetate 95+%
5g
$ 698.00

Alichem
(1-Benzyl-4-oxo-piperidin-3-yl)-aceticacidethylester
5g
$ 792.48

Total 5 raw suppliers

Chemical Property of (1-Benzyl-4-oxo-piperidin-3-yl)-acetic acid ethyl ester

Chemical Property:

Vapor Pressure:2.29E-06mmHg at 25°C
Boiling Point:392.5°C at 760 mmHg
Flash Point:191.2°C
PSA：46.61000
Density:1.117g/cm³
LogP:1.96870
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:275.15214353
Heavy Atom Count:20
Complexity:337

Purity/Quality:: Ethyl2-(1-benzyl-4-oxopiperidin-3-yl)acetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1CN(CCC1=O)CC2=CC=CC=C2

Technology Process of (1-Benzyl-4-oxo-piperidin-3-yl)-acetic acid ethyl ester

There total 1 articles about (1-Benzyl-4-oxo-piperidin-3-yl)-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 3612-20-2
1-phenylmethyl-4-piperidone

: 105-36-2
ethyl bromoacetate

: 6947-75-7
(1-benzyl-4-oxopiperidin-3-yl)acetic acid ethyl ester

Guidance literature:: 1-phenylmethyl-4-piperidone; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 0.166667h; Inert atmosphere;

ethyl bromoacetate; In tetrahydrofuran; hexane; at -78 ℃; for 3h; Inert atmosphere;
DOI:10.1021/jm101376k

Reference yield: 90.0%

: 400877-05-6
(1‐methyl‐1H‐pyrazol‐4‐yl)methanamine

: 6947-75-7
(1-benzyl-4-oxopiperidin-3-yl)acetic acid ethyl ester

: C₂₁H₃₀N₄O₂

Guidance literature:: (1‐methyl‐1H‐pyrazol‐4‐yl)methanamine; (1-benzyl-4-oxopiperidin-3-yl)acetic acid ethyl ester; With acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 0.5h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; Inert atmosphere;