3-(4-Fluorophenyl)-2,6-diphenylpyrimidin-4(3H)-one

Base Information

Chemical Name:3-(4-Fluorophenyl)-2,6-diphenylpyrimidin-4(3H)-one
CAS No.:89069-78-3
Molecular Formula:C22H15FN2O
Molecular Weight:342.372
Hs Code.:
DSSTox Substance ID:DTXSID70534403
Wikidata:Q82408199

Synonyms:89069-78-3;3-(4-Fluorophenyl)-2,6-diphenylpyrimidin-4(3H)-one;DTXSID70534403

Suppliers and Price of 3-(4-Fluorophenyl)-2,6-diphenylpyrimidin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-(4-Fluorophenyl)-2,6-diphenylpyrimidin-4(3H)-one

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:342.11684127
Heavy Atom Count:26
Complexity:565

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=O)N(C(=N2)C3=CC=CC=C3)C4=CC=C(C=C4)F

Technology Process of 3-(4-Fluorophenyl)-2,6-diphenylpyrimidin-4(3H)-one

There total 4 articles about 3-(4-Fluorophenyl)-2,6-diphenylpyrimidin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 21719-88-0
N′-(4-fluorophenyl)benzamidine

: 2216-94-6
phenylpropynoic acid ethyl ester

: 89069-78-3
3-(4-fluorophenyl)-2,6-diphenyl-4(3H)-pyrimidinone

Guidance literature:: In ethanol; at 150 ℃; for 2h; Inert atmosphere; Microwave irradiation; Green chemistry;
DOI:10.14233/ajchem.2019.21784

Reference yield: 58.0%

: 21719-88-0
N′-(4-fluorophenyl)benzamidine

: 89069-78-3
3-(4-fluorophenyl)-2,6-diphenyl-4(3H)-pyrimidinone

Guidance literature:: at 80 ℃; for 96h;

Reference yield:

: 100-47-0
benzonitrile

: 89069-78-3
3-(4-fluorophenyl)-2,6-diphenyl-4(3H)-pyrimidinone

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / dimethyl sulfoxide / 2 h / 20 °C / Inert atmosphere

2: ethanol / 2 h / 150 °C / Inert atmosphere; Microwave irradiation; Green chemistry

With sodium hydride; In ethanol; dimethyl sulfoxide;
DOI:10.14233/ajchem.2019.21784