2-Ethoxy-5,6-dihydro[1,1'-biphenyl]-3(4H)-one

Base Information

Chemical Name:2-Ethoxy-5,6-dihydro[1,1'-biphenyl]-3(4H)-one
CAS No.:89114-51-2
Molecular Formula:C14H16O2
Molecular Weight:216.28
Hs Code.:
DSSTox Substance ID:DTXSID70526767
Nikkaji Number:J974.733H
Wikidata:Q82395565

Synonyms:89114-51-2;2-Ethoxy-5,6-dihydro[1,1'-biphenyl]-3(4H)-one;DTXSID70526767

Suppliers and Price of 2-Ethoxy-5,6-dihydro[1,1'-biphenyl]-3(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Ethoxy-5,6-dihydro[1,1'-biphenyl]-3(4H)-one

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:216.115029749
Heavy Atom Count:16
Complexity:285

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(CCCC1=O)C2=CC=CC=C2

Technology Process of 2-Ethoxy-5,6-dihydro[1,1'-biphenyl]-3(4H)-one

There total 3 articles about 2-Ethoxy-5,6-dihydro[1,1'-biphenyl]-3(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 108-86-1,52753-63-6
bromobenzene

: 29941-82-0
2-ethoxycyclohex-2-en-1-one

: 89114-51-2
2-Ethoxy-3-phenyl-cyclohex-2-enone

Guidance literature:: With water; N-ethyl-N,N-diisopropylamine; triphenylphosphine; palladium diacetate; In N,N-dimethyl-formamide; at 100 ℃; for 16h;
DOI:10.1021/jo980221b

Reference yield: 40.0%

: 70871-45-3
2-hydroxy-3-phenyl-2-cyclohexen-1-one

: 89114-51-2
2-Ethoxy-3-phenyl-cyclohex-2-enone

Guidance literature:: With potassium carbonate; In acetone; for 6h; Heating;
DOI:10.1021/jo00373a015

Reference yield:

: 10316-66-2
2-hydroxy-2-cyclohexen-1-one

: 89114-51-2
2-Ethoxy-3-phenyl-cyclohex-2-enone

Guidance literature:: Multi-step reaction with 2 steps

1: 42 percent / p-TsOH*H₂O / benzene / 16 h / Heating

2: 86 percent / iPr₂NEt, Ph₃P, H₂O / Pd(OAc)2 / dimethylformamide / 16 h / 100 °C

With water; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; triphenylphosphine; palladium diacetate; In N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo980221b