10316-66-2

Basic information

• Product Name: 2-Cyclohexen-1-one, 2-hydroxy-
• Synonyms: 2-Cyclohexen-1-one, 2-hydroxy-
• CAS NO: 10316-66-2
• Molecular Formula: C₆H₈O₂
• Molecular Weight: 112.12700
• Mol File: 10316-66-2.mol
• Article Data: 8

Chemical Properties

• Melting Point: 30 °C
• Boiling Point: 256.6 °C at 760 mmHg
• Flash Point: 106.2 °C
• Appearance: /
• Density: 1.229 g/cm³
• Vapor Pressure: 0.00228mmHg at 25°C
• Refractive Index: 1.548
• PKA: 8.82±0.20(Predicted)
• CAS DataBase Reference: 2-Cyclohexen-1-one, 2-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexen-1-one, 2-hydroxy-(10316-66-2)
• EPA Substance Registry System: 2-Cyclohexen-1-one, 2-hydroxy-(10316-66-2)

Safety Data

• Hazardous Substances Data: 10316-66-2(Hazardous Substances Data)

Usage

General Description

2-Cyclohexen-1-one, 2-hydroxy- is a chemical compound with the molecular formula C6H8O2. It is an organic compound with a cyclic structure containing a hydroxyl group attached to a cyclohexenone ring. 2-Cyclohexen-1-one, 2-hydroxy- is commonly used in organic synthesis and as a reagent in chemical reactions. It is also known for its potential medicinal and pharmaceutical applications, including the development of anti-inflammatory and anticancer drugs. Additionally, it has been studied for its potential use in the production of flavor and fragrance compounds due to its aromatic properties.

InChI:InChI=1/C6H8O2/c7-5-3-1-2-4-6(5)8/h3,7H,1-2,4H2

Upstream product

• 533-60-8 cyclohexanone-2-ol 
• 34006-70-7 2,6-dibromocyclohexanone 
• 137934-95-3 2-hydroxy-3-methoxycyclohexanone 
• 6838-67-1 1,2-bis(trimethylsilyloxy)cyclohex-1-ene 
• 108-94-1 cyclohexanone 
• 1460-57-7 trans-1,2-cyclohexandiol 
• 29836-41-7 2-[[[(1-hydroxy-6-oxo-2-cyclohexen-1-yl)carbonyl]hydroxy]methyl]phenyl-β-D-glucopyranoside 
• 1792-81-0 cis-1,2-cyclohexane 
• 6705-49-3 7-oxabicyclo[4.1.0]heptan-2-one 

Downstream Products

• 110-94-1 1,5-pentanedioic acid 
• 5746-02-1 5-oxopentanoic acid 
• 627-91-8 adipic acid monomethyl ester 
• 6719-33-1 5,5-dimethoxy-1-oxopentanoic acid 
• 86544-11-8 methyl 5-carboxy-2-hydroxypentanoate 
• 6710-26-5 5,5-diethoxy-valeric acid 
• 102066-11-5 2-cyclohex-2-enone 
• 102066-12-6 2-cyclohex-2-enone 
• 109324-59-6 N-Isopropyl-3-methyl-N-(6-oxo-cyclohex-1-enyl)-butyramide 
• 93831-71-1 N-isopropyl-N-2-(1-oxocyclohex-2-enyl)-cyclohexanecarboxamide 
• 93831-73-3 N-Isopropyl-N-(6-oxo-cyclohex-1-enyl)-2-phenyl-acetamide 
• 83505-28-6 2-(allyloxy)cyclohex-2-en-1-one 
• 109324-50-7 N-Methyl-N-(6-oxo-cyclohex-1-enyl)-2-phenyl-acetamide 
• 70871-46-4 2-hydroxy-3-(4-methylphenyl)-2-cyclohexen-1-one 

Relevant articles and documents

Oxidation of Vicinal Diols to α-Dicarbonyl Compounds by Trifluoroacetic Anhydride "Activated" Dimethyl Sulfoxide

Trifluoroacetic anhydride "activated" dimethyl sulfoxide is an effective oxidant for the conversion of vicinal diols into the corresponding α-dicarbonyl compounds or products derived therefrom.Unlike the Swern oxidant, the title reagent system gives good yields of products derived from halogenated substrates.The method has permitted syntheses of previously inaccessible compounds including tropolones, a ?-homo-o-benzoquinone, and a "hyperreactive" α-keto aldehyde.

Microwave-assisted synthesis of α-hydroxy ketone and α-diketone and pyrazine derivatives from α-halo and α,α′-dibromo ketone

A novel reaction of α-halo ketone (α-bromo and α-chloro ketone) with irradiation under microwave gave the corresponding α-hydroxyketone and pyrazine derivative in good yields. In the case of α,α′-dibromo ketone, α-diketone was obtained. This reaction affords a new, clean and convenient synthetic method for α-hydroxyketone, α-diketone, α-chloro ketone and pyrazine derivative.

Acid Catalyzed Alcoholysis of an Epoxide and Reactions of Products on Contact with Silica Gel

The alcoholysis of epoxide 1 in acidic methanol leads to various products; one of these - hydroxymethoxyketone 7 - rearranges to the isomeric ketone 14 on contact with silica gel. Keywords: Cleavage of Epoxide, Rearrangement

A New Synthesis of 3-Alkyl-1,2-cyclohexanediones from 2-Alkylcyclohexanones Using Iodine/Copper(II) Acetate

The reactions of 2-alkyl-, 2,5-dimethyl-, and 3,3,5-trimethylcyclohexanone with iodine/copper(II) acetate in boiling aqueous acetic acid gave the respective 3-alkyl-, 3,6-dimethyl-, and 3,5,5-trimethyl-1,2-cyclohexanediones in 40-70percent yields.This new