(-)-Isopinocampheol

Base Information

• Chemical Name: (-)-Isopinocampheol
• CAS No.: 1196-00-5
• Molecular Formula: C10H18 O
• Molecular Weight: 154.252
• European Community (EC) Number: 214-806-7,247-011-9
• DSSTox Substance ID: DTXSID001315705
• Nikkaji Number: J203.466B
• Wikidata: Q104375906
• Mol file: 1196-00-5.mol

Synonyms:(-)-Isopinocampheol;1196-00-5;l-Isopinocampheol;(1R,2R,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol;Isopinocampheol;25465-65-0;(1R,2R,3R,5S)-(-)-Isopinocampheol;EINECS 214-806-7;(1R-(1alpha,2beta,3alpha,5alpha))-2,6,6-Trimethylbicyclo(3.1.1)heptan-3-ol;CC1(C)C2CC(O)C(C)C1C2;[1R-(1alpha,2beta,3alpha,5alpha)]-2,6,6-trimethylbicyclo[3.1.1]heptan-3-ol;SCHEMBL596648;(1R,2R,3R,5S)-2,6,6-Trimethylbicyclo[ 3.1.1 ]heptan-3-ol;REPVLJRCJUVQFA-BZNPZCIMSA-N;DTXSID001315705;AC3157;AKOS040744585;AS-0229;(1R,2R,3R,5S)-(-)-Isopinocampheol, 98%;EN300-19632128;J-500019;(1R,2R,3R,5S)-2,6,6-trimethylbicyclo-[3.1.1]heptan-3-ol

Chemical Property of (-)-Isopinocampheol

Chemical Property:

• Vapor Pressure: 0.0292mmHg at 25°C
• Melting Point: 52-55 °C
• Boiling Point: 219 °C(lit.)
• PKA: 15.35±0.60(Predicted)
• Flash Point: 200 °F
• PSA: 20.23000
• Density: 0.96g/cm³
• LogP: 2.04940
• Storage Temp.: Refrigerator
• Solubility.: Benzene (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly),
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 154.135765193
• Heavy Atom Count: 11
• Complexity: 174

Purity/Quality:

97% ^*data from raw suppliers

l-Isopinocampheol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C2CC(C2(C)C)CC1O
• Isomeric SMILES: C[C@@H]1[C@H]2C[C@H](C2(C)C)C[C@H]1O
• Uses: l-Isopinocampheol is a monoterpene and a component of several plant essential oils, showed dual viricidal activity against herpes simplex virus 1 (HSV-1).

Technology Process of (-)-Isopinocampheol

There total 63 articles about (-)-Isopinocampheol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

aminodiisopinocampheylborane → (-)-isopinocampheol (1196-00-5)

Guidance literature:

With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1039/c6cc06151f

Reference yield: 90.0%

(-)-α-pinene (7785-26-4,25766-18-1) → (+)-isopinocampheol (1196-00-5,2734-31-8,19889-94-2,19889-95-3,25465-65-0,25465-95-6,27779-29-9,35997-96-7,35998-01-7,36129-11-0,51152-11-5,73366-08-2,125473-76-9,473-61-0,24041-60-9)

Guidance literature:

(-)-α-pinene; With dimethylsulfide borane complex; In tetrahydrofuran; at 20 ℃;

With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; ethanol; for 1h; Heating;

DOI:10.1016/S0957-4166(99)00446-2

Reference yield: 89.0%

diisopinocampheylborane (21932-54-7) → (-)-isopinocampheol (1196-00-5)

Guidance literature:

With methanol; In tetrahydrofuran;

diisopinocampheylborane; With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; at 20 - 45 ℃;

DOI:10.1016/S0040-4020(99)00272-0

upstream raw materials:

(-)-trans-pinocarveol

2,3-epoxy-cis-pinane

Pinene

(+)-α-pinene

Downstream raw materials:

phthalic acid mono-((1R:2R:3R)-pinanyl-⁽³⁾-ester)

(1R,2R,5S)-2,6,6-trimethylbicyclo[3.1.1]heptan-3-one

(-)-isopinocampheyl acetate

trans-N,N'-diisobutyryl-p-menthane-1,8-diamine