(4-Nitrophenyl)(2,3,4-trimethoxyphenyl)methanone

Base Information

Chemical Name:(4-Nitrophenyl)(2,3,4-trimethoxyphenyl)methanone
CAS No.:6342-95-6
Molecular Formula:C16H15NO6
Molecular Weight:317.2934
Hs Code.:
NSC Number:46675
DSSTox Substance ID:DTXSID20286622
Wikidata:Q82022395
ChEMBL ID:CHEMBL1882743

Synonyms:6342-95-6;MLS002667085;(4-nitrophenyl)(2,3,4-trimethoxyphenyl)methanone;HMS3088H22;NSC46675;CHEMBL1882743;DTXSID20286622;NSC-46675;SMR001556857

Suppliers and Price of (4-Nitrophenyl)(2,3,4-trimethoxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (4-Nitrophenyl)(2,3,4-trimethoxyphenyl)methanone

Chemical Property:

Vapor Pressure:9.36E-11mmHg at 25°C
Boiling Point:516°Cat760mmHg
Flash Point:225°C
Density:1.262g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:317.08993720
Heavy Atom Count:23
Complexity:415

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)C(=O)C2=CC=C(C=C2)[N+](=O)[O-])OC)OC

Technology Process of (4-Nitrophenyl)(2,3,4-trimethoxyphenyl)methanone

There total 2 articles about (4-Nitrophenyl)(2,3,4-trimethoxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1449505-57-0
(2-hydroxy-3,4-dimethoxyphenyl)(4-nitrophenyl)methanone

: 77-78-1
dimethyl sulfate

: 6342-95-6
(4-nitrophenyl)(2,3,4-trimethoxyphenyl)methanone

Guidance literature:: With potassium carbonate; In acetone; for 18h; Reflux;
DOI:10.1039/c2ra22391k

Reference yield:

: 634-36-6
1,2,3-trimethoxybenzene

: 62-23-7
4-nitro-benzoic acid

: 6342-95-6
(4-nitrophenyl)(2,3,4-trimethoxyphenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate; trifluoroacetic anhydride / 1,2-dichloro-ethane / 18 h / Reflux

2: potassium carbonate / acetone / 18 h / Reflux

With boron trifluoride diethyl etherate; potassium carbonate; trifluoroacetic anhydride; In 1,2-dichloro-ethane; acetone; 1: |Friedel-Crafts Acylation;
DOI:10.1039/c2ra22391k

Reference yield: 32.0%

: 6342-95-6
(4-nitrophenyl)(2,3,4-trimethoxyphenyl)methanone

: 1779-49-3
Methyltriphenylphosphonium bromide

: 1449505-62-7
2-(4-nitrophenyl)-1-(2,3,4-trimethoxyphenyl)ethanone

Guidance literature:: Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 1h;

(4-nitrophenyl)(2,3,4-trimethoxyphenyl)methanone; In tetrahydrofuran; at 20 ℃;
DOI:10.1039/c2ra22391k