2'-Fluoroacetophenone

Base Information

Chemical Name:2'-Fluoroacetophenone
CAS No.:445-27-2
Molecular Formula:C8H7FO
Molecular Weight:138.141
Hs Code.:29147090
NSC Number:88297
DSSTox Substance ID:DTXSID50196200
Nikkaji Number:J196.137C
Wikidata:Q72479014
Mol file:445-27-2.mol

Synonyms:o-fluoroacetophenone

Suppliers and Price of 2'-Fluoroacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2''-Fluoroacetophenone
1g
$ 55.00

TCI Chemical
2'-Fluoroacetophenone >97.0%(GC)
25g
$ 17.00

TCI Chemical
2'-Fluoroacetophenone >97.0%(GC)
5g
$ 11.00

SynQuest Laboratories
2'-Fluoroacetophenone 97%
100 g
$ 40.00

SynQuest Laboratories
2'-Fluoroacetophenone 97%
5 g
$ 10.00

SynQuest Laboratories
2'-Fluoroacetophenone 97%
500 g
$ 140.00

SynQuest Laboratories
2'-Fluoroacetophenone 97%
25 g
$ 15.00

Sigma-Aldrich
2′-Fluoroacetophenone 97%
5g
$ 67.20

Matrix Scientific
2'-Fluoroacetophenone 97%
25g
$ 9.00

Matrix Scientific
2'-Fluoroacetophenone 97%
100g
$ 37.00

Total 157 raw suppliers

Chemical Property of 2'-Fluoroacetophenone

Chemical Property:

Appearance/Colour:Clear colorless to light yellow or light green
Melting Point:26-27 °C
Refractive Index:n20/D 1.507(lit.)
Boiling Point:180.8 °C at 760 mmHg
Flash Point:67.5 °C
PSA：17.07000
Density:1.103 g/cm³
LogP:2.02830
Storage Temp.:Store below +30°C.
Solubility.:Soluble in Acetone, Chloroform, Dichloromethane, Ethanol, Ethyl
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:138.048093005
Heavy Atom Count:10
Complexity:133

Purity/Quality:

99% ^*data from raw suppliers

2''-Fluoroacetophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37/39-37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(=O)C1=CC=CC=C1F
Uses 2'-Fluoroacetophenone is used as starting reagent in the synthesis of ascididemin. It is used to produce 1-(2-piperidin-1-yl-phenyl)-ethanone by reaction with piperidine.

Technology Process of 2'-Fluoroacetophenone

There total 46 articles about 2'-Fluoroacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 445-26-1
1-(2-fluorophenyl)ethanol

: 445-27-2
2'-Fluoroacetophenone

Guidance literature:: With [(2-(benzoimidazol-2-yl)-6-(3,5-dimethylpyrazol-1-yl)pyridine)RuCl₂(PPh₃)]; potassium tert-butylate; acetone; In methanol; at 56 ℃; for 0.5h; under 750.075 Torr; Catalytic behavior; Inert atmosphere;
DOI:10.1016/j.tetlet.2014.01.072

Reference yield: 97.0%

: 344-73-0
1-fluoro-2-(prop-1-en-2-yl)benzene

: 445-27-2
2'-Fluoroacetophenone

Guidance literature:: With iron(III) trifluoromethanesulfonate; C₆₅H₇₇N₅O₄S₂; oxygen; In 1,2-dichloro-ethane; at 75 ℃; for 24h; under 760.051 Torr; chemoselective reaction; Green chemistry;
DOI:10.1021/jacs.5b03956

Reference yield: 90.0%

: 917-54-4
methyllithium

: 445-29-4
o-fluoro-benzoic acid

: 445-27-2
2'-Fluoroacetophenone

Guidance literature:: methyllithium; With copper(l) cyanide; In diethyl ether; at 0 ℃; for 0.0833333h; Inert atmosphere;

o-fluoro-benzoic acid; In diethyl ether; at 0 - 20 ℃; for 15h; Inert atmosphere;
DOI:10.1021/ol202237j