Cyclopropa[c]pyrrolo[3,2-e]indole-7-carboxylicacid,1,2,4,5,8,8a-hexahydro-2-[(2E)-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-6-methyl-4-oxo-,methyl ester, (7bR,8S)- (9CI)

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Chemical Name:Cyclopropa[c]pyrrolo[3,2-e]indole-7-carboxylicacid,1,2,4,5,8,8a-hexahydro-2-[(2E)-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-6-methyl-4-oxo-,methyl ester, (7bR,8S)- (9CI)
CAS No.:153925-99-6
Molecular Formula:C24H22 N2 O5
Molecular Weight:418.449
Hs Code.:

Cyclopropa[c]pyrrolo[3,2-e]indole-7-carboxylicacid,1,2,4,5,8,8a-hexahydro-2-[(2E)-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-6-methyl-4-oxo-,methyl ester, (7bR,8S)- (9CI)

Synonyms:Cyclopropa[c]pyrrolo[3,2-e]indole-7-carboxylicacid,1,2,4,5,8,8a-hexahydro-2-[3-(4-methoxyphenyl)-1-oxo-2-propenyl]-6-methyl-4-oxo-,methyl ester, [7bR-[2(E),7bR*,8S*]]-

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Chemical Property of Cyclopropa[c]pyrrolo[3,2-e]indole-7-carboxylicacid,1,2,4,5,8,8a-hexahydro-2-[(2E)-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-6-methyl-4-oxo-,methyl ester, (7bR,8S)- (9CI)

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Technology Process of Cyclopropa[c]pyrrolo[3,2-e]indole-7-carboxylicacid,1,2,4,5,8,8a-hexahydro-2-[(2E)-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-6-methyl-4-oxo-,methyl ester, (7bR,8S)- (9CI)

There total 5 articles about Cyclopropa[c]pyrrolo[3,2-e]indole-7-carboxylicacid,1,2,4,5,8,8a-hexahydro-2-[(2E)-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-6-methyl-4-oxo-,methyl ester, (7bR,8S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 153925-97-4,134106-68-6
3-methoxycarbonyl-2-methylduocarmycin A

: 153925-99-6
C₂₄H₂₂N₂O₅

Guidance literature:: Multi-step reaction with 2 steps

1: methanol

2: NaH

With sodium hydride; In methanol; 1: Hydrolysis / 2: Acylation;
DOI:10.1016/S0968-0896(99)00293-X

Reference yield:

: 89023-01-8
p-nitrophenyl ester of 4-methoxycinnamic acid

: 186760-22-5
CPI

: 153925-99-6
C₂₄H₂₂N₂O₅

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, -50 deg C, 3 h, 2.) DMF, -50 deg C, 1 h;
DOI:10.1021/jm9606094

Reference yield:

: 8-bromomethyl-6-[3-(4-methoxy-phenyl)-acryloyl]-2-methyl-4-(4-methyl-piperazin-1-ylcarbamoyloxy)-3,6,7,8-tetrahydro-3,6-diaza-as-indacene-1-carboxylic acid methyl ester; compound with GENERIC INORGANIC NEUTRAL COMPONENT

: 153925-99-6
C₂₄H₂₂N₂O₅

Guidance literature:: With mouse serum; at 37 ℃; for 0.5h; pH=7.4; Further Variations:; Reagents; Temperatures; Product distribution; Enzymatic reaction;
DOI:10.1016/S0968-0896(99)00293-X