(2Z)-3-[(1H-Benzimidazol-2-yl)methyl]-2-(phenylimino)-1,3-thiazolidin-4-one

Base Information

Chemical Name:(2Z)-3-[(1H-Benzimidazol-2-yl)methyl]-2-(phenylimino)-1,3-thiazolidin-4-one
CAS No.:89334-78-1
Molecular Formula:C17H14N4OS
Molecular Weight:322.38400
Hs Code.:
DSSTox Substance ID:DTXSID20526398

Synonyms:89334-78-1;3-((1H-Benzo[d]imidazol-2-yl)methyl)-2-(phenylimino)thiazolidin-4-one;DTXSID20526398;(2Z)-3-[(1H-Benzimidazol-2-yl)methyl]-2-(phenylimino)-1,3-thiazolidin-4-one;3-[(1h-benzo[d]imidazol-2-yl) methyl]-2-(phenylimino) thiazolidin-4-one

Suppliers and Price of (2Z)-3-[(1H-Benzimidazol-2-yl)methyl]-2-(phenylimino)-1,3-thiazolidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2Z)-3-[(1H-Benzimidazol-2-yl)methyl]-2-(phenylimino)-1,3-thiazolidin-4-one

Chemical Property:

PSA：86.65000
LogP:3.26390
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:322.08883226
Heavy Atom Count:23
Complexity:477

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(=O)N(C(=NC2=CC=CC=C2)S1)CC3=NC4=CC=CC=C4N3

Technology Process of (2Z)-3-[(1H-Benzimidazol-2-yl)methyl]-2-(phenylimino)-1,3-thiazolidin-4-one

There total 5 articles about (2Z)-3-[(1H-Benzimidazol-2-yl)methyl]-2-(phenylimino)-1,3-thiazolidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 77523-95-6
1-[(1H-benzo[d]imidazol-2-yl) methyl]-3-phenylthiourea

: 79-11-8
chloroacetic acid

: 89334-78-1
3-[(1H-benzo[d]imidazol-2-yl) methyl]-2-(phenylimino)thiazolidin-4-one

Guidance literature:: With sodium acetate; In ethanol; for 4h; Heating;

Reference yield: 79.0%

: 77523-95-6
1-[(1H-benzo[d]imidazol-2-yl) methyl]-3-phenylthiourea

: 105-36-2
ethyl bromoacetate

: 89334-78-1
3-[(1H-benzo[d]imidazol-2-yl) methyl]-2-(phenylimino)thiazolidin-4-one

Guidance literature:: In ethanol; Reflux;
DOI:10.1007/s00044-012-0057-3

Reference yield:

: 5993-91-9
2-(aminomethyl)benzimidazole dihydrochloride

: 89334-78-1
3-[(1H-benzo[d]imidazol-2-yl) methyl]-2-(phenylimino)thiazolidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / NaHCO₃ / ethanol / 6 h / Heating

2: 97 percent / CH₃COONa / ethanol / 4 h / Heating

With sodium acetate; sodium hydrogencarbonate; In ethanol;