4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-bromophenyl)amino]-

Base Information

Chemical Name:4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-bromophenyl)amino]-
CAS No.:89374-42-5
Molecular Formula:C13H8BrN3OS
Molecular Weight:334.196
Hs Code.:
DSSTox Substance ID:DTXSID70411760
Wikidata:Q82218702

Synonyms:89374-42-5;4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-bromophenyl)amino]-;SCHEMBL7097002;DTXSID70411760;ZDSHFPFHPYNHGV-UHFFFAOYSA-N;2-(4-bromoanilino)-4H-pyrido[3,2-e]-1,3-thiazin-4-one

Suppliers and Price of 4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-bromophenyl)amino]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-bromophenyl)amino]-

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:332.95715
Heavy Atom Count:19
Complexity:382

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(N=C1)SC(=NC2=O)NC3=CC=C(C=C3)Br

Technology Process of 4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-bromophenyl)amino]-

There total 5 articles about 4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-bromophenyl)amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 89374-30-1
1-(4-Bromophenyl)-3-(2-chloronicotinoyl)thiourea

: 89374-42-5
2-[(4-bromophenyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one

Guidance literature:: In toluene; for 4h; Reflux;
DOI:10.1016/j.bmc.2015.02.033

Reference yield: 33.6%

: C₁₃H₁₀BrN₃OS

: 89374-42-5
2-[(4-bromophenyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one

Guidance literature:: In ethanol; for 0.5h; Reflux;

Reference yield:

: 2942-59-8
2-chloronicotinic acid

: 89374-42-5
2-[(4-bromophenyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: N,N-dimethyl-formamide; thionyl chloride / 1.5 h / Reflux

1.2: 0.5 h / 20 °C

2.1: acetone / 0.67 h / 20 °C

3.1: toluene / 4 h / Reflux

With thionyl chloride; N,N-dimethyl-formamide; In acetone; toluene;
DOI:10.1016/j.bmc.2015.02.033