8-Chloro-1-(2-fluorophenyl)-3H-2-benzazepine

Base Information

Chemical Name:8-Chloro-1-(2-fluorophenyl)-3H-2-benzazepine
CAS No.:89376-31-8
Molecular Formula:C16H11ClFN
Molecular Weight:271.71700
Hs Code.:
DSSTox Substance ID:DTXSID50533631

Synonyms:8-Chloro-1-(2-fluorophenyl)-3H-2-benzazepine;89376-31-8;DTXSID50533631;8-Chloro-1-(2-fluoro-phenyl)-3H-benzo[c]azepine

Suppliers and Price of 8-Chloro-1-(2-fluorophenyl)-3H-2-benzazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 8-Chloro-1-(2-fluorophenyl)-3H-2-benzazepine

Chemical Property:

Melting Point:87-88 °C
Boiling Point:373.2±42.0 °C(Predicted)
PSA：12.36000
Density:1.22±0.1 g/cm3(Predicted)
LogP:3.77890
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:271.0564052
Heavy Atom Count:19
Complexity:379

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C=CC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F

Technology Process of 8-Chloro-1-(2-fluorophenyl)-3H-2-benzazepine

There total 4 articles about 8-Chloro-1-(2-fluorophenyl)-3H-2-benzazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 1.0%

: 101713-23-9
8-chloro-1-(2-fluorophenyl)-4,5-dibromo-4,5-dihydro-3H-2-benzazepine

: 101713-27-3
8-chloro-1-(2-fluorophenyl)-3-(1,1,-dimethylethoxy)-3H-2-benzazepine

: 89376-31-8
8-chloro-1-(2-fluorophenyl)-3H-2-benzazepine

: 737712-15-1
5-bromo-8-chloro-1-(2-fluorophenyl)-3H-2-benzazepine

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; tert-butyl alcohol; for 1.25h; Yield given; Ambient temperature;
DOI:10.1021/jo00362a007

Reference yield: 1.0%

: 101713-23-9
8-chloro-1-(2-fluorophenyl)-4,5-dibromo-4,5-dihydro-3H-2-benzazepine

: 75-65-0
tert-butyl alcohol

: 101713-27-3
8-chloro-1-(2-fluorophenyl)-3-(1,1,-dimethylethoxy)-3H-2-benzazepine

: 89376-31-8
8-chloro-1-(2-fluorophenyl)-3H-2-benzazepine

: 737712-15-1
5-bromo-8-chloro-1-(2-fluorophenyl)-3H-2-benzazepine

Guidance literature:: With potassium hydroxide; In tetrahydrofuran; for 1.25h; Ambient temperature;
DOI:10.1021/jo00362a007

Reference yield:

: 76049-63-3
3-Amino-1-[4-chloro-2-(2-fluorobenzoyl)phenyl]propyne

: 89376-31-8
8-chloro-1-(2-fluorophenyl)-3H-2-benzazepine

Guidance literature:: With barium sulfate; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; under 760 Torr; Ambient temperature;
DOI:10.1021/jo00362a007