Butanoic acid, 1-phenylethyl ester, (R)-

Base Information

• Chemical Name: Butanoic acid, 1-phenylethyl ester, (R)-
• CAS No.: 89378-61-0
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Mol file: 89378-61-0.mol

Synonyms:

Chemical Property of Butanoic acid, 1-phenylethyl ester, (R)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Butanoic acid, 1-phenylethyl ester, (R)-

There total 43 articles about Butanoic acid, 1-phenylethyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

isopropyl butyrate (638-11-9) + 1-Phenylethanol (98-85-1,13323-81-4) → (S)-1-phenylethanol (1445-91-6) + (R)-1-phenylethanol (1517-69-7) + (R)-1-phenylethyl butyrate (89378-61-0)

Guidance literature:

With immobilized Candida antarctica Lipase B; potassium carbonate; chiral ruthenium-based; In toluene; at 70 ℃; for 24h; under 150.012 Torr;

DOI:10.1016/j.tetasy.2006.08.003

Reference yield: 86.0%

butanoic acid anhydride (106-31-0) + 1-Phenylethanol (98-85-1,13323-81-4) → R/S-α-methylbenzyl n-butyrate (89378-61-0,122407-72-1,3460-44-4)

Guidance literature:

With Cl^(1-)*C₅H₁₄NO⁽¹⁺⁾*3ZnCl₂; In neat (no solvent); at 20 ℃; for 0.5h; Green chemistry;

DOI:10.1039/c6ra22757k

Reference yield: 39.0%

butyl butyrate (109-21-7) + 1-Phenylethanol (98-85-1,13323-81-4) → R/S-α-methylbenzyl n-butyrate (89378-61-0,122407-72-1,3460-44-4)

Guidance literature:

With carbonylhydrido[6-(di-tert-butylphosphinomethylene)-2-(N,N-diethylaminomethyl)-1,6-dihydropyridine]ruthenium(II); In toluene; for 36h; Inert atmosphere; Reflux;

DOI:10.1002/adsc.201000663

upstream raw materials:

1-Phenylethanol

butyryl chloride

acetophenonazine

butyric acid

Downstream raw materials:

butanamide

(R)-1-phenylethanol

(S)-α-methylbenzyl butyrate

(S)-1-phenylethanol