1-(4-Butoxy-2-butenyl)-4-phenyl-4-piperidinol propionate hydrochloride

Base Information

Chemical Name:1-(4-Butoxy-2-butenyl)-4-phenyl-4-piperidinol propionate hydrochloride
CAS No.:78033-80-4
Molecular Formula:C22H33 N O3 . Cl H
Molecular Weight:395.97
Hs Code.:
Mol file:78033-80-4.mol

Synonyms:1-(4-Butoxy-2-butenyl)-4-phenyl-4-piperidinol propionate hydrochloride;1-(4'-n-Butoxybuten-2'-yl)-4-phenyl-4-propionyloxypiperidine hydrochloride;1-(4-Butoxy-2-butenyl)-4-phenyl-4-piperidinol propionate (ester) hydrochloride;4-Piperidinol, 1-(4-butoxy-2-butenyl)-4-phenyl-, propionate (ester), hydrochloride;LS-116864

Suppliers and Price of 1-(4-Butoxy-2-butenyl)-4-phenyl-4-piperidinol propionate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4-BUTOXY-2-BUTENYL)-4-PHENYL-4-PIPERIDINOL PROPIONATE HYDROCHLORIDE 95.00%
5MG
$ 505.78

Total 1 raw suppliers

Chemical Property of 1-(4-Butoxy-2-butenyl)-4-phenyl-4-piperidinol propionate hydrochloride

Chemical Property:

Vapor Pressure:1.55E-08mmHg at 25°C
Melting Point:136-137 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
Boiling Point:457°C at 760 mmHg
Flash Point:230.2°C
PSA：38.77000
LogP:5.04370
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:11
Exact Mass:395.2227216
Heavy Atom Count:27
Complexity:421

Purity/Quality:: 1-(4-BUTOXY-2-BUTENYL)-4-PHENYL-4-PIPERIDINOL PROPIONATE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCOCC=CCN1CCC(CC1)(C2=CC=CC=C2)OC(=O)CC.Cl
Isomeric SMILES:CCCCOC/C=C/CN1CCC(CC1)(C2=CC=CC=C2)OC(=O)CC.Cl

Technology Process of 1-(4-Butoxy-2-butenyl)-4-phenyl-4-piperidinol propionate hydrochloride

There total 5 articles about 1-(4-Butoxy-2-butenyl)-4-phenyl-4-piperidinol propionate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.4%

: 78033-79-1
1-(4'-n-Butoxybutyn-2'-yl)-4-phenyl-4-propionyloxypiperidine hydrochloride

: 78033-80-4
1-(4'-n-Butoxybuten-2'-yl)-4-phenyl-4-propionyloxypiperidine hydrochloride

Guidance literature:: With hydrogen; Lindlar's catalyst; In ethanol; at 21 ℃; for 0.116667h;
DOI:10.1007/BF01152326

Reference yield:

: 40807-61-2
4-hydroxy-4-phenylpiperidin

: 78033-80-4
1-(4'-n-Butoxybuten-2'-yl)-4-phenyl-4-propionyloxypiperidine hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 82.4 percent / CuCl / dioxane / 4 h / 100 °C

2: propionic acid / 3.5 h / 95 °C

3: HCl / diethyl ether / 0 °C

4: 93.4 percent / H₂ / 5percent Pd/CaCO₃ / ethanol / 0.12 h / 21 °C

With hydrogenchloride; hydrogen; propionic acid; copper(l) chloride; Lindlar's catalyst; In 1,4-dioxane; diethyl ether; ethanol;
DOI:10.1007/BF01152326

Reference yield:

: 78033-77-9
1-(4'-n-Butoxybutyn-2'-yl)-4-phenyl-4-hydroxypiperidine

: 78033-80-4
1-(4'-n-Butoxybuten-2'-yl)-4-phenyl-4-propionyloxypiperidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: propionic acid / 3.5 h / 95 °C

2: HCl / diethyl ether / 0 °C

3: 93.4 percent / H₂ / 5percent Pd/CaCO₃ / ethanol / 0.12 h / 21 °C

With hydrogenchloride; hydrogen; propionic acid; Lindlar's catalyst; In diethyl ether; ethanol;
DOI:10.1007/BF01152326