1-(4-Butoxy-2-butynyl)-4-phenyl-4-piperidinol propionate hydrochloride

Base Information

Chemical Name:1-(4-Butoxy-2-butynyl)-4-phenyl-4-piperidinol propionate hydrochloride
CAS No.:78033-79-1
Molecular Formula:C22H32ClNO3
Molecular Weight:393.954
Hs Code.:
DSSTox Substance ID:DTXSID40228680

Synonyms:1-(4-Butoxy-2-butynyl)-4-phenyl-4-piperidinol propionate hydrochloride;4-Piperidinol, 1-(4-butoxy-2-butynyl)-4-phenyl-, propionate (ester), hydrochloride;1-(4'-n-Butoxybutyn-2'-yl)-4-phenyl-propionyloxypiperidine hydrochloride;1-(4'-n-Butoxybutyn-2'yl)-4-phenyl-4-propionyloxypiperidine hydrochloride;1-(4-Butoxy-2-butynyl)-4-phenyl-4-piperidinol propionate (ester) hydrochloride;78033-79-1;DTXSID40228680;LS-116865

Suppliers and Price of 1-(4-Butoxy-2-butynyl)-4-phenyl-4-piperidinol propionate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 1-(4-Butoxy-2-butynyl)-4-phenyl-4-piperidinol propionate hydrochloride

Chemical Property:

Vapor Pressure:6.11E-09mmHg at 25°C
Boiling Point:468.2°Cat760mmHg
Flash Point:237°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:393.2070716
Heavy Atom Count:27
Complexity:476

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCOCC#CCN1CCC(CC1)(C2=CC=CC=C2)OC(=O)CC.Cl

Technology Process of 1-(4-Butoxy-2-butynyl)-4-phenyl-4-piperidinol propionate hydrochloride

There total 4 articles about 1-(4-Butoxy-2-butynyl)-4-phenyl-4-piperidinol propionate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78033-78-0
1-(4'-n-Butoxybutyn-2'-yl)-4-phenyl-4-propionyloxypiperidine

: 78033-79-1
1-(4'-n-Butoxybutyn-2'-yl)-4-phenyl-4-propionyloxypiperidine hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; at 0 ℃; Yield given;
DOI:10.1007/BF01152326

Reference yield:

: 40807-61-2
4-hydroxy-4-phenylpiperidin

: 78033-79-1
1-(4'-n-Butoxybutyn-2'-yl)-4-phenyl-4-propionyloxypiperidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 82.4 percent / CuCl / dioxane / 4 h / 100 °C

2: propionic acid / 3.5 h / 95 °C

3: HCl / diethyl ether / 0 °C

With hydrogenchloride; propionic acid; copper(l) chloride; In 1,4-dioxane; diethyl ether;
DOI:10.1007/BF01152326

Reference yield:

: 78033-77-9
1-(4'-n-Butoxybutyn-2'-yl)-4-phenyl-4-hydroxypiperidine

: 78033-79-1
1-(4'-n-Butoxybutyn-2'-yl)-4-phenyl-4-propionyloxypiperidine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: propionic acid / 3.5 h / 95 °C

2: HCl / diethyl ether / 0 °C

With hydrogenchloride; propionic acid; In diethyl ether;
DOI:10.1007/BF01152326