Ethyl (3E)-3-[(4-bromo-2-methoxyphenyl)imino]butanoate

Base Information

Chemical Name:Ethyl (3E)-3-[(4-bromo-2-methoxyphenyl)imino]butanoate
CAS No.:89446-10-6
Molecular Formula:C13H16BrNO3
Molecular Weight:314.179
Hs Code.:
DSSTox Substance ID:DTXSID30561775

Synonyms:89446-10-6;SCHEMBL9828774;DTXSID30561775;Ethyl (3E)-3-[(4-bromo-2-methoxyphenyl)imino]butanoate

Suppliers and Price of Ethyl (3E)-3-[(4-bromo-2-methoxyphenyl)imino]butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Ethyl (3E)-3-[(4-bromo-2-methoxyphenyl)imino]butanoate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:313.03136
Heavy Atom Count:18
Complexity:307

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(=NC1=C(C=C(C=C1)Br)OC)C

Technology Process of Ethyl (3E)-3-[(4-bromo-2-methoxyphenyl)imino]butanoate

There total 2 articles about Ethyl (3E)-3-[(4-bromo-2-methoxyphenyl)imino]butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 59557-91-4
4-bromo-2-methoxyaniline

: 141-97-9
ethyl acetoacetate

: 89446-10-6
ethyl 3-<(4-bromo-2-methoxyphenyl)imino>butyrate

Guidance literature:: With calcium sulfate; acetic acid; In ethanol; for 4h; Heating;
DOI:10.1021/jm00128a041

Reference yield:

: 90-04-0
2-methoxy-phenylamine

: 89446-10-6
ethyl 3-<(4-bromo-2-methoxyphenyl)imino>butyrate

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / 2,4,4,6-tetrabromo-2,5-cyclohexadienone / CH₂Cl₂ / -5 deg C to RT

2: 79 percent / glacial HOAc, drierite / ethanol / 4 h / Heating

With calcium sulfate; 2,4,4,6-Tetrabromo-2,5-cyclohexadien-1-one; acetic acid; In ethanol; dichloromethane;
DOI:10.1021/jm00128a041

Reference yield:

: 89446-10-6
ethyl 3-<(4-bromo-2-methoxyphenyl)imino>butyrate

: 2-(4,8dimethoxy-2-methyl-6-quinolyl-methyl)-3-anilinoacrylonitrile

Guidance literature:: Multi-step reaction with 5 steps

1: 70.5 percent / diphenyl ether / 0.42 h / 255 °C

2: 93 percent / POCl₃ / 2 h / Heating

3: 86 percent / methanol / 5 h / 120 °C

4: 1) THF, hexane, -70 deg C, 2 min, 2) to -40 deg C

5: NaOMe

With sodium methylate; trichlorophosphate; In methanol; diphenylether;
DOI:10.1021/jm00128a041