Carbamic acid, [6-[[3-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)propyl]amino]hexyl]-, phenylmethyl ester, monohydrobromide

Base Information

• Chemical Name: Carbamic acid, [6-[[3-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)propyl]amino]hexyl]-, phenylmethyl ester, monohydrobromide
• CAS No.: 89450-72-6
• Molecular Formula: BrH*C₂₁H₃₀N₄O₄
• Molecular Weight: 483.406
• Mol file: 89450-72-6.mol

Synonyms:

Chemical Property of Carbamic acid, [6-[[3-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)propyl]amino]hexyl]-, phenylmethyl ester, monohydrobromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [6-[[3-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)propyl]amino]hexyl]-, phenylmethyl ester, monohydrobromide

There total 3 articles about Carbamic acid, [6-[[3-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)propyl]amino]hexyl]-, phenylmethyl ester, monohydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

monobenzyloxycarbonyl hexamethylenediamine hydrochloride (78618-06-1) + 1-(3-bromopropyl)uracil (22917-77-7) → N-<3-(1-uracilyl)propyl>-N'-carbobenzoxyhexamethylenediamine hydrobromide (89450-72-6)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide;

DOI:10.1007/BF00515364

Reference yield:

1,6-Hexanediamine (124-09-4) → N-<3-(1-uracilyl)propyl>-N'-carbobenzoxyhexamethylenediamine hydrobromide (89450-72-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 0.1 N NaOH

2: HCl / acetic acid

3: 58 percent / triethylamine / dimethylformamide

With hydrogenchloride; sodium hydroxide; triethylamine; In acetic acid; N,N-dimethyl-formamide;

DOI:10.1007/BF00515364

Reference yield:

N1,N8-Dicarbobenzoxyhexanediamine (16644-57-8) → N-<3-(1-uracilyl)propyl>-N'-carbobenzoxyhexamethylenediamine hydrobromide (89450-72-6)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl / acetic acid

2: 58 percent / triethylamine / dimethylformamide

With hydrogenchloride; triethylamine; In acetic acid; N,N-dimethyl-formamide;

DOI:10.1007/BF00515364

upstream raw materials:

monobenzyloxycarbonyl hexamethylenediamine hydrochloride

1-(3-bromopropyl)uracil

1,6-Hexanediamine

N¹,N⁸-Dicarbobenzoxyhexanediamine