Benzyl (6-aminohexyl)carbamate hydrochloride

Base Information

Chemical Name:Benzyl (6-aminohexyl)carbamate hydrochloride
CAS No.:78618-06-1
Molecular Formula:C14H22 N2 O2 . Cl H
Molecular Weight:286.8
Hs Code.:
European Community (EC) Number:625-075-2
ChEMBL ID:CHEMBL1083156
DSSTox Substance ID:DTXSID10526423
Mol file:78618-06-1.mol

Synonyms:78618-06-1;Benzyl (6-aminohexyl)carbamate hydrochloride;N-Carbobenzoxy-1,6-diaminohexane Hydrochloride;Benzyl N-(6-aminohexyl)carbamate hydrochloride;benzyl N-(6-aminohexyl)carbamate;hydrochloride;N-1-Z-1,6-diaminohexane HCl;MFCD00270151;N-Carbobenzoxy-1,6-diaminohexane HCl;N-1-Z-1,6-diaminohexane . HCl;Z-1,6-diaminohexane HCl;N-Z-1,6-hexanediamine hydrochloride;N-Cbz-1,6-diaminohexane HCl;SCHEMBL6375520;CHEMBL1083156;DTXSID10526423;Z-NH-(CH2)6-NH2.HCl;AKOS015847948;N-Cbz-1,6-diaminohexane Hydrochloride;AS-66218;N1-Cbz-hexane-1,6-diamine Hydrochloride;SY112040;BENZYL (6-AMINOHEXYL)CARBAMATE HCL;CS-0149755;A12850;N-Z-1,6-hexanediamine hydrochloride, >=97% (AT);Benzyl (6-aminohexyl)carbamate--hydrogen chloride (1/1);N-(6-Aminohexyl)carbamic Acid Benzyl Ester Hydrochloride;N1-Benzyloxycarbonyl-1,6-hexamethylenediamine hydrochloride

Suppliers and Price of Benzyl (6-aminohexyl)carbamate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Carbobenzoxy-1,6-diaminohexane Hydrochloride
50mg
$ 45.00

TCI Chemical
N-Carbobenzoxy-1,6-diaminohexane Hydrochloride >98.0%(HPLC)(N)
1g
$ 115.00

TCI Chemical
N-Carbobenzoxy-1,6-diaminohexane Hydrochloride >98.0%(HPLC)(N)
5g
$ 349.00

Sigma-Aldrich
N-Z-1,6-hexanediamine hydrochloride ≥97% (AT)
1g
$ 119.00

Crysdot
Benzyl(6-aminohexyl)carbamatehydrochloride 97%
10g
$ 476.00

Chem-Impex
Z-1,6-diaminohexanehydrochloride,≥98%(HPLC) ≥98%(HPLC)
5G
$ 302.85

Chem-Impex
Z-1,6-diaminohexanehydrochloride,≥98%(HPLC) ≥98%(HPLC)
1G
$ 75.71

Chem-Impex
Z-1,6-diaminohexanehydrochloride,≥98%(HPLC) ≥98%(HPLC)
10G
$ 553.28

Biosynth Carbosynth
Z-1,6-diaminohexane·HCl
5 g
$ 325.00

Biosynth Carbosynth
Z-1,6-diaminohexane·HCl
10 g
$ 550.00

Total 18 raw suppliers

Chemical Property of Benzyl (6-aminohexyl)carbamate hydrochloride

Chemical Property:

Vapor Pressure:4.93E-08mmHg at 25°C
Melting Point:175-180 °C
Boiling Point:436.8°C at 760 mmHg
Flash Point:218°C
PSA：64.35000
LogP:4.32510
Storage Temp.:Store at 0°C
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:9
Exact Mass:286.1448057
Heavy Atom Count:19
Complexity:216

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Carbobenzoxy-1,6-diaminohexane Hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NCCCCCCN.Cl
Uses Introduction of a hexamethylenediamine linker

Technology Process of Benzyl (6-aminohexyl)carbamate hydrochloride

There total 7 articles about Benzyl (6-aminohexyl)carbamate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: (6-azido-hexyl)-carbamic acid benzyl ester

: 78618-06-1
monobenzyloxycarbonyl hexamethylenediamine hydrochloride

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; water; at 20 ℃; for 24h;
DOI:10.1016/S0040-4039(01)00282-9

Reference yield: 35.0%

: 124-09-4
1,6-Hexanediamine

: 501-53-1,94274-21-2
benzyl chloroformate

: 78618-06-1
monobenzyloxycarbonyl hexamethylenediamine hydrochloride

Guidance literature:: With hydrogenchloride; 1.) methanol, 18 h; 2.) dichloromethane, 0 deg C;
DOI:10.1016/0008-6215(83)88217-2

Reference yield:

: 629-03-8
1 ,6-dibromohexane

: 78618-06-1
monobenzyloxycarbonyl hexamethylenediamine hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 99 percent / NaN₃ / dimethylformamide; H₂O / 20 h / 80 °C

2: 60 percent / Ph₃P; HCl / diethyl ether; ethyl acetate; H₂O / 24 h / 20 °C

3: 100 percent / NaOH / tetrahydrofuran; H₂O / 12 h / 0 - 20 °C

4: 94 percent / Ph₃P / tetrahydrofuran; H₂O / 24 h / 20 °C

With hydrogenchloride; sodium hydroxide; sodium azide; triphenylphosphine; In tetrahydrofuran; diethyl ether; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)00282-9