2(1H)-Pyridinone, 5-chloro-1-[(4,6-diphenyl-2-pyridinyl)carbonyl]-

Base Information

• Chemical Name: 2(1H)-Pyridinone, 5-chloro-1-[(4,6-diphenyl-2-pyridinyl)carbonyl]-
• CAS No.: 89478-74-0
• Molecular Formula: C23H15ClN2O2
• Molecular Weight: 386.837
• DSSTox Substance ID: DTXSID10395818
• Wikidata: Q82196118
• Mol file: 89478-74-0.mol

Synonyms:2(1H)-Pyridinone, 5-chloro-1-[(4,6-diphenyl-2-pyridinyl)carbonyl]-;89478-74-0;DTXSID10395818

Chemical Property of 2(1H)-Pyridinone, 5-chloro-1-[(4,6-diphenyl-2-pyridinyl)carbonyl]-

Chemical Property:

• Melting Point: 152-154 °C
• Boiling Point: 592.0±50.0 °C(Predicted)
• PSA: 51.96000
• Density: 1.38±0.1 g/cm3(Predicted)
• LogP: 4.91920
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 386.0822054
• Heavy Atom Count: 28
• Complexity: 647

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC(=NC(=C2)C(=O)N3C=C(C=CC3=O)Cl)C4=CC=CC=C4

Technology Process of 2(1H)-Pyridinone, 5-chloro-1-[(4,6-diphenyl-2-pyridinyl)carbonyl]-

There total 2 articles about 2(1H)-Pyridinone, 5-chloro-1-[(4,6-diphenyl-2-pyridinyl)carbonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(ethoxycarbonyl)-4,6-diphenylpyrylium tetrafluoroborate → 5-chloro-1-(4,6-diphenyl-2-pyridylcarbonyl)-2-pyridone (89478-74-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / CH₂Cl₂ / 15 h / 25 °C

2: 1.) aq. sodium hydroxide, 2.) hydrochloric acid (pH 2) / 1.) 25 deg C, 48 h, 2.) 0 deg C --> 25 deg C, 2 h

With hydrogenchloride; sodium hydroxide; In dichloromethane;

DOI:10.1039/P19830002623

Reference yield:

C25H20ClN2O2(1+)*BF4(1-) → 5-chloro-1-(4,6-diphenyl-2-pyridylcarbonyl)-2-pyridone (89478-74-0)

Guidance literature:

With hydrogenchloride; sodium hydroxide; Yield given. Multistep reaction; 1.) 25 deg C, 48 h, 2.) 0 deg C --> 25 deg C, 2 h;

DOI:10.1039/P19830002623

Reference yield: 95.0%

5-chloro-1-(4,6-diphenyl-2-pyridylcarbonyl)-2-pyridone (89478-74-0) → 5-chloro-1,2-dihydropyridin-2-one (4214-79-3) + 2-(ethoxycarbonyl)-4,6-diphenylpyridine (80560-56-1)

Guidance literature:

With hydrogenchloride; ethanol; Heating;

DOI:10.1039/P19830002623

Downstream raw materials:

5-chloro-1,2-dihydropyridin-2-one

2-(ethoxycarbonyl)-4,6-diphenylpyridine

4,6-diphenyl-2-(t-butylcarbamoyl)pyridine

2,4-diphenylpicolinic acid