2-Pyridinecarboxamide, N-(1,1-dimethylethyl)-4,6-diphenyl-

Base Information

Chemical Name:2-Pyridinecarboxamide, N-(1,1-dimethylethyl)-4,6-diphenyl-
CAS No.:89478-85-3
Molecular Formula:C22H22N2O
Molecular Weight:330.429
Hs Code.:
DSSTox Substance ID:DTXSID00395923

Synonyms:2-Pyridinecarboxamide, N-(1,1-dimethylethyl)-4,6-diphenyl-;89478-85-3;DTXSID00395923

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Pyridinecarboxamide, N-(1,1-dimethylethyl)-4,6-diphenyl-

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:330.173213330
Heavy Atom Count:25
Complexity:430

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)NC(=O)C1=CC(=CC(=N1)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 2-Pyridinecarboxamide, N-(1,1-dimethylethyl)-4,6-diphenyl-

There total 4 articles about 2-Pyridinecarboxamide, N-(1,1-dimethylethyl)-4,6-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 89478-74-0
5-chloro-1-(4,6-diphenyl-2-pyridylcarbonyl)-2-pyridone

: 4214-79-3
5-chloro-1,2-dihydropyridin-2-one

: 89478-85-3
4,6-diphenyl-2-(t-butylcarbamoyl)pyridine

Guidance literature:: With tert-butylamine; In chloroform; for 6h; Heating;
DOI:10.1039/P19830002623

Reference yield: 70.0%

: 89478-74-0
5-chloro-1-(4,6-diphenyl-2-pyridylcarbonyl)-2-pyridone

: 75-64-9
tert-butylamine

: 4214-79-3
5-chloro-1,2-dihydropyridin-2-one

: 89478-85-3
4,6-diphenyl-2-(t-butylcarbamoyl)pyridine

Guidance literature:: In chloroform; for 6h; Heating;
DOI:10.1039/P19830002623

Reference yield:

: 2-(ethoxycarbonyl)-4,6-diphenylpyrylium tetrafluoroborate

: 89478-85-3
4,6-diphenyl-2-(t-butylcarbamoyl)pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / CH₂Cl₂ / 15 h / 25 °C

2: 1.) aq. sodium hydroxide, 2.) hydrochloric acid (pH 2) / 1.) 25 deg C, 48 h, 2.) 0 deg C --> 25 deg C, 2 h

3: 70 percent / t-butylamine / CHCl₃ / 6 h / Heating

With hydrogenchloride; sodium hydroxide; tert-butylamine; In dichloromethane; chloroform;
DOI:10.1039/P19830002623