2-(2,4,6-TRIMETHYLBENZOYL)BENZOIC ACID

Base Information

• Chemical Name: 2-(2,4,6-TRIMETHYLBENZOYL)BENZOIC ACID
• CAS No.: 2346-67-0
• Molecular Formula: C17H16 O3
• Molecular Weight: 268.312
• Hs Code.: 2918300090
• Mol file: 2346-67-0.mol

Synonyms:Benzoicacid, o-(2,4,6-trimethylbenzoyl)- (6CI,7CI); 2-(2,4,6-Trimethylbenzoyl)benzoicacid; NSC 408487; o-Mesitoylbenzoic acid

Chemical Property of 2-(2,4,6-TRIMETHYLBENZOYL)BENZOIC ACID

Chemical Property:

• Vapor Pressure: 2.84E-08mmHg at 25°C
• Boiling Point: 433.2°Cat760mmHg
• Flash Point: 229.9°C
• PSA: 54.37000
• Density: 1.172g/cm³
• LogP: 3.54100

Purity/Quality:

99% ^*data from raw suppliers

2-(2,4,6-TRIMETHYLBENZOYL)BENZOIC ACID Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2,4,6-TRIMETHYLBENZOYL)BENZOIC ACID

There total 4 articles about 2-(2,4,6-TRIMETHYLBENZOYL)BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

phthalic anhydride (85-44-9) + 1,3,5-trimethyl-benzene (108-67-8) → 2-(2,4,6-trimethylbenzoyl)-benzoic acid (2346-67-0)

Guidance literature:

With [bmim]Cl*AlCl₃; at 45 ℃; for 6h;

Reference yield: 82.0%

mesitylglyoxylic acid (3112-46-7) + benzoic acid (65-85-0,8013-63-6) → 2-(2,4,6-trimethylbenzoyl)-benzoic acid (2346-67-0)

Guidance literature:

With palladium(II) trifluoroacetate; silver carbonate; In 1,2-dimethoxyethane; at 165 ℃; for 48h; chemoselective reaction; Sealed tube;

DOI:10.1021/ol400919u

Reference yield:

Phthaloyl dichloride (88-95-9) + 1,3,5-trimethyl-benzene (108-67-8) → 2-(2,4,6-trimethylbenzoyl)-benzoic acid (2346-67-0)

Guidance literature:

With silver perchlorate;

DOI:10.1039/jr9570001718

upstream raw materials:

phthalic anhydride

1,3,5-trimethyl-benzene

Phthaloyl dichloride

mesitylglyoxylic acid

Downstream raw materials:

3-mesitylisobenzofuran-1(3H)-one

2-mesityl-4H-benzo[d][1,3]oxazin-4-one

N-mesityl-phthalamic acid

4-(2,4,6-trimethylphenyl)-2,3-phthalazin-1-one

Refernces

• 1、 El-Hashash, Maher A.,El-Kady, Ahmed Y.,Taha, Mamdouh A.,El-Shamy, Ibrahim E.. "Synthesis and antimicrobial activity of some condensed [4-(2,4,6- trimethylphenyl)-1(2H)-oxo-phthalazin-2-yl]acetic acid hydrazide". body text. p. 616 - 626. Retrieved 2012/05/05.
• 2、 Mohile, Swapnil S.,Potdar, Mahesh K.,Salunkhe, Manikrao M.. "An alternative route to syntheses of aryl keto acids in a chloroaluminate ionic liquid". . p. 650 - 651. Retrieved 2007/10/03.