4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid

Base Information

Chemical Name:4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid
CAS No.:89524-63-0
Molecular Formula:C₁₁H₅ClF₃NO₂
Molecular Weight:275.614
Hs Code.:2933499090
DSSTox Substance ID:DTXSID20547801
Wikidata:Q82426266
Mol file:89524-63-0.mol

Synonyms:89524-63-0;4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ACID;SCHEMBL4466003;DTXSID20547801;PACCRSUMCGBTBO-UHFFFAOYSA-N;AKOS026751542;SB68885;A850705;4-Chloro-7-trifluoromethyl quinoline-3-carboxylic acid;4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLICACID

Suppliers and Price of 4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
4-chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid 95
1g
$ 533.00

Labseeker
4-chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid 95
10g
$ 1783.00

Labseeker
4-chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid 95
5g
$ 1200.00

Crysdot
4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylicacid 97%
5g
$ 1022.00

Chemenu
4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylicacid 97%
5g
$ 963.00

Alichem
4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylicacid
25g
$ 3517.50

Alichem
4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylicacid
10g
$ 2336.96

Total 8 raw suppliers

Chemical Property of 4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid

Chemical Property:

PSA：50.19000
LogP:3.60520
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:274.9960906
Heavy Atom Count:18
Complexity:337

Purity/Quality:

97% ^*data from raw suppliers

4-chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=CN=C2C=C1C(F)(F)F)C(=O)O)Cl

Technology Process of 4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid

There total 3 articles about 4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-chloro-7-trifluoromethyl quinoline

: 108-18-9
diisopropylamine

: 89524-63-0
4-chloro-7-(trifluoromethyl)-3-quinolinecarboxylic acid

Guidance literature:: With hydrogenchloride; n-butyllithium; nitrogen; In tetrahydrofuran; sodium hydroxide; hexane; chloroform; water;

Reference yield:

: 346-55-4
4-chloro-7-trifluoromethyl quinoline

: 124-38-9,18923-20-1
carbon dioxide

: 89524-63-0
4-chloro-7-(trifluoromethyl)-3-quinolinecarboxylic acid

Guidance literature:: With n-butyllithium; diisopropylamine; Yield given. Multistep reaction; 1) THF, hexane, -70 to -60 deg C, 20 min, 2) r.t., overnight;
DOI:10.1021/jm00129a026