2-isobutyl-1,4-diMethoxybenzene

Base Information

• Chemical Name: 2-isobutyl-1,4-diMethoxybenzene
• CAS No.: 89556-61-6
• Molecular Formula: C12H18O2
• Molecular Weight: 194.274
• DSSTox Substance ID: DTXSID20601735
• Wikidata: Q82498538
• Mol file: 89556-61-6.mol

Synonyms:2-isobutyl-1,4-diMethoxybenzene;89556-61-6;Benzene, 1,4-dimethoxy-2-(2-methylpropyl)-;1,4-dimethoxy-2-(2-methylpropyl)benzene;SCHEMBL4960829;DTXSID20601735;AKOS032947887

Chemical Property of 2-isobutyl-1,4-diMethoxybenzene

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 194.130679813
• Heavy Atom Count: 14
• Complexity: 156

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)CC1=C(C=CC(=C1)OC)OC

Technology Process of 2-isobutyl-1,4-diMethoxybenzene

There total 5 articles about 2-isobutyl-1,4-diMethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-(2,5-dimethoxyphenyl)-2-methylpropene (35205-30-2) → 1-(2,5-dimethoxyphenyl)-2-methylpropane (89556-61-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 3h; under 2585.7 Torr;

DOI:10.1021/jm00372a015

Reference yield:

1-(2,5-dimethoxyphenyl)-2-methyl-1-propanol (26172-15-6) → 1-(2,5-dimethoxyphenyl)-2-methylpropane (89556-61-6)

Guidance literature:

Multi-step reaction with 2 steps

1: cation exchange resin (Amberlyst-15) / benzene / 1.5 h / Heating

2: 100 percent / H₂ / 5percent Pd/C / ethanol / 3 h / 2585.7 Torr

With cation exchange resin (Amberlyst-15); hydrogen; palladium on activated charcoal; In ethanol; benzene;

DOI:10.1021/jm00372a015

Reference yield:

2',5'-dimethoxy-2-methylpropiophenone (89556-60-5) → 1-(2,5-dimethoxyphenyl)-2-methylpropane (89556-61-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 72 percent / NaBH₄ / ethanol / 2.5 h / Ambient temperature

2: cation exchange resin (Amberlyst-15) / benzene / 1.5 h / Heating

3: 100 percent / H₂ / 5percent Pd/C / ethanol / 3 h / 2585.7 Torr

With sodium tetrahydroborate; cation exchange resin (Amberlyst-15); hydrogen; palladium on activated charcoal; In ethanol; benzene;

DOI:10.1021/jm00372a015

upstream raw materials:

1-(2,5-dimethoxyphenyl)-2-methylpropene

1-(2,5-dimethoxyphenyl)-2-methyl-1-propanol

2',5'-dimethoxy-2-methylpropiophenone

1,4-dimethoxybezene

Downstream raw materials:

1-<2,5-dimethoxy-4-(2-methylpropyl)phenyl>-2-nitropropene

1-<2,5-dimethoxy-4-(2-methylpropyl)phenyl>-2-aminopropane

2-isobutyl-p-benzoquinone

5,5'-diisobutyl-2,2'-bis-p-benzoquinone

Refernces