89556-60-5

Usage

Uses

Intermediate in the synthesis of various pharmaceuticals and organic compounds; key building block in the production of psychoactive drugs; potential therapeutic properties in treating mental and emotional disorders; reagent for organic synthesis in organic chemistry research; potential pharmacological effects.

Upstream product

• 79-30-1 isobutyryl chloride 
• 150-78-7 1,4-dimethoxybezene 
• 79-31-2 isobutyric Acid 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 155628-88-9 1-(2',5'-dimethoxyphenyl)prop-2-en-1-ol 
• 67-56-1 methanol 

Downstream Products

• 74587-20-5 2-pivaloyl-1,4-bezoquinone 
• 35459-97-3 2',5'-dihydroxypivalophenone 
• 89556-70-7 1-<2,5-dimethoxy-4-(2-methylpropyl)phenyl>-2-aminopropane 
• 89556-63-8 1-<2,5-dimethoxy-4-(2-methylpropyl)phenyl>-2-nitropropene 
• 89556-62-7 2,5-dimethoxy-4-(2-methylpropyl)benzaldehyde 
• 35205-30-2 1-(2,5-dimethoxyphenyl)-2-methylpropene 
• 89556-61-6 1-(2,5-dimethoxyphenyl)-2-methylpropane 
• 73566-49-1 isobutyryl-1,4-benzoquinone 
• 39868-14-9 2,5-Dimethoxyphenyl tert-butyl ketone 
• 112450-27-8 1-(2,5-dihydroxy-phenyl)-2-methyl-propan-1-one 
• 26172-15-6 1-(2,5-dimethoxyphenyl)-2-methyl-1-propanol 
• 109497-49-6 5-(2,5-dimethoxy-phenyl)-4-methyl-[1,2]dithiol-3-thione 

Relevant academic research and scientific papers

Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol

One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.

Intramolecular Cycloaddition of Two Acyl-1,4-benzoquinone Moieties on Photolysis

Upon irradiation a regio- and stereoselective cycloaddition occured intramolecularly between two acyl-1,4-benzoquinone moieties connected by a polymethylene bridge.The regio- and stereoselectivities are different from those of the corresponding intermolecular cycloaddition; this was interpreted in terms of the Diels-Alder reaction between an acyl-1,4-benzoquinone moiety and a photochemically produced dienol.

Substituent Branching in Phenethylamine-Type Hallucinogens: A Comparison of 1--2-aminopropane and 1--2-aminopropane

Two novel hallucinogen analogues related to 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM, STP) were synthesized and evaluated in the two-lever drug discrimination paradigm by using 0.08 mg/kg of LSD at the training drug stimulus.The two compounds

Benzoquinones and Related Compounds. Part 2. Preferred Conformations of Some Acyl-1,4-benzoquinones in Solution

Studies based on polarographic reduction potentials, electronic absorption spectra, and (1)H and (13)C nuclear magnetic relaxation data show that in solution the preferred conformation of formyl-1,4-benzoquinone is that with the formyl and quinonoid groups coplanar, and the formyl carbonyl group anti to the 1-carbonyl, whereas that of acetyl- and pivaloyl-1,4-benzoquinone has the acyl groups approximately perpendicular to the quinonoid ring.