Adenosine, 2'-deoxy-2-fluoro-

Base Information

Chemical Name:Adenosine, 2'-deoxy-2-fluoro-
CAS No.:21679-12-9
Molecular Formula:C10H12 F N5 O3
Molecular Weight:269.235
Hs Code.:2934999090
NSC Number:123799,114093
DSSTox Substance ID:DTXSID30944281
Mol file:21679-12-9.mol

Synonyms:Adenosine, 2'-deoxy-2-fluoro-;21679-13-0;9-(2-deoxypentofuranosyl)-2-fluoro-9h-purin-6-amine;CHEMBL279654;SCHEMBL23982169;DTXSID30944281;BDBM50008363;NSC114093;NSC123799;NSC-123799;PD042436;FT-0774800

Suppliers and Price of Adenosine, 2'-deoxy-2-fluoro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-2’-deoxyadenosine
250mg
$ 690.00

SynQuest Laboratories
2'-Deoxy-2-fluoroadenosine 96%
100 mg
$ 115.00

SynQuest Laboratories
2'-Deoxy-2-fluoroadenosine 96%
250 mg
$ 195.00

SynQuest Laboratories
2'-Deoxy-2-fluoroadenosine 96%
1 g
$ 425.00

SynQuest Laboratories
2'-Deoxy-2-fluoroadenosine 96%
5 g
$ 1795.00

Sigma-Aldrich
2-Fluoro-2′-deoxyadenosine 96%
250mg
$ 259.00

Crysdot
(2R,3S,5R)-5-(6-Amino-2-fluoro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol 97%
1g
$ 640.00

Chemenu
(2R,3S,5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol 97%
1g
$ 604.00

Biosynth Carbosynth
2'-Deoxy-2-fluoroadenosine
1 g
$ 375.00

Biosynth Carbosynth
2'-Deoxy-2-fluoroadenosine
500 mg
$ 195.00

Total 22 raw suppliers

Chemical Property of Adenosine, 2'-deoxy-2-fluoro-

Chemical Property:

Appearance/Colour:white to of-white crystals
Melting Point:218 °C (dec.)
Boiling Point:696.7 °C at 760 mmHg
Flash Point:375.1 °C
PSA：119.31000
Density:2.01 g/cm³
LogP:-0.23050
XLogP3:0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:269.09241742
Heavy Atom Count:19
Complexity:338

Purity/Quality:

97% ^*data from raw suppliers

2-Fluoro-2’-deoxyadenosine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36/37/38
Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1C(C(OC1N2C=NC3=C(N=C(N=C32)F)N)CO)O
Uses 2-Fluoro-2’-deoxyadenosine is an analog tested to the susceptibility of clinical metronidazole-resistant Trichomonas vaginalis. Also, it is one of two purine nucleoside that forms a suicide system as a powerful killing and bystander effects on tumor cells.

Technology Process of Adenosine, 2'-deoxy-2-fluoro-

There total 18 articles about Adenosine, 2'-deoxy-2-fluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 259528-01-3
2'-deoxy-2-fluoro-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenosine

: 21679-12-9
2-fluoro-2'-deoxyadenosine

Guidance literature:: With tetraethylammonium fluoride; In acetonitrile; at 20 ℃; for 0.5h;
DOI:10.1080/15257770008035007

Reference yield: 87.0%

: 675598-20-6
2-fluoro-9-(3,5-bis[O-(t-butyldimethylsilyl)]-2-deoxy-D-erythro-pentofuranosyl)adenine

: 21679-12-9
2-fluoro-2'-deoxyadenosine

Guidance literature:: With tetraethylammonium fluoride; In acetone; at 20 ℃;
DOI:10.1081/NCN-120025237

Reference yield: 74.0%

: 951-78-0,63844-76-8
2'-deoxyuridine

: 700-49-2
2-fluoroadenine

: 21679-12-9
2-fluoro-2'-deoxyadenosine

Guidance literature:: With aeromonas hydrophila CECT 4226; at 45 ℃; for 1h; pH=7; aq. phosphate buffer; Enzymatic reaction;
DOI:10.3109/10242422.2010.538949